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Table 3 Subgroup analysis for asthma during four-year follow-up (2010–2013) according to body mass index and waist circumference by sex

From: Sex differences in the association between asthma incidence and modifiable risk factors in Korean middle-aged and older adults: NHIS-HEALS 10-year cohort

 

Men

Women

Case/N

HR (95% CI)

Case/N

HR (95% CI)

Body Mass Index (BMI)

 Underweight (< 18.5 kg/m2)

160/2706

1.18 (1.01–1.39)

129/2353

0.95 (0.79–1.13)

 Normal (18.5–< 23 kg/m2)

2182/47659

–

2306/40929

–

 Overweight (23–< 25 kg/m2)

1846/42599

0.98 (0.92–1.05)

1683/27415

1.08 (1.01–1.15)

 Obesity (25–< 30 kg/m2)

2214/48073

1.07 (1.01–1.13)

1967/28287

1.21 (1.13–1.28)

 Severe obesity (≥30 kg/m2)

155/2987

1.23 (1.05–1.45)

222/3011

1.28 (1.12–1.47)

Waist circumference (WC)

Men

Women

    

  < 80 cm

  < 75 cm

1451/33521

–

1796/33307

–

 80–< 90 cm

 75–< 85 cm

3435/77420

1.05 (0.99–1.12)

2985/46929

1.14 (1.08–1.21)

 90–< 100 cm

 85–< 95 cm

1483/29954

1.13 (1.05–1.21)

1314/18686

1.23 (1.14–1.32)

  ≥ 100 cm

  ≥ 95 cm

188/3129

1.34 (1.16–1.57)

212/3073

1.19 (1.03–1.37)

Combination of BMI & WC

 No abdominal obesity & Underweight/Normal (< 23 kg/m2)

2292/49523

–

2368/42074

–

 No abdominal obesity & Overweight (23–< 25 kg/m2)

1548/37389

0.95 (0.89–1.01)

1427/23721

1.07 (1.00–1.14)

 No abdominal obesity & Obesity (≥25 kg/m2)

1046/24029

1.04 (0.96–1.12)

986/14441

1.21 (1.12–1.30)

 Abdominal obesity * & Underweight/Normal (< 23 kg/m2)

50/842

1.08 (0.82–1.43)

67/1208

0.90 (0.71–1.15)

 Abdominal obesity * & Overweight (23–< 25 kg/m2)

298/5210

1.15 (1.02–1.29)

256/3694

1.15 (1.01–1.31)

 Abdominal obesity * & Obesity (≥25 kg/m2)

1323/27031

1.09 (1.02–1.17)

1203/16857

1.22 (1.13–1.31)

  1. Subgroup analysis was performed using BMI and waist circumference measured in 2008/2009 excluding subjects with asthma diagnosis before the follow-up period. Separate models were developed for BMI, WC and the combination of BMI and WC after adjusting for age, insurance type, household income, smoking, drinking and physical activity
  2. * Abdominal obesity was defined as waist circumference > 100 cm in men or 95 cm in women