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Table 3 Subgroup analysis for asthma during four-year follow-up (2010–2013) according to body mass index and waist circumference by sex

From: Sex differences in the association between asthma incidence and modifiable risk factors in Korean middle-aged and older adults: NHIS-HEALS 10-year cohort

  Men Women
Case/N HR (95% CI) Case/N HR (95% CI)
Body Mass Index (BMI)
 Underweight (< 18.5 kg/m2) 160/2706 1.18 (1.01–1.39) 129/2353 0.95 (0.79–1.13)
 Normal (18.5–< 23 kg/m2) 2182/47659 2306/40929
 Overweight (23–< 25 kg/m2) 1846/42599 0.98 (0.92–1.05) 1683/27415 1.08 (1.01–1.15)
 Obesity (25–< 30 kg/m2) 2214/48073 1.07 (1.01–1.13) 1967/28287 1.21 (1.13–1.28)
 Severe obesity (≥30 kg/m2) 155/2987 1.23 (1.05–1.45) 222/3011 1.28 (1.12–1.47)
Waist circumference (WC)
Men Women     
  < 80 cm   < 75 cm 1451/33521 1796/33307
 80–< 90 cm  75–< 85 cm 3435/77420 1.05 (0.99–1.12) 2985/46929 1.14 (1.08–1.21)
 90–< 100 cm  85–< 95 cm 1483/29954 1.13 (1.05–1.21) 1314/18686 1.23 (1.14–1.32)
  ≥ 100 cm   ≥ 95 cm 188/3129 1.34 (1.16–1.57) 212/3073 1.19 (1.03–1.37)
Combination of BMI & WC
 No abdominal obesity & Underweight/Normal (< 23 kg/m2) 2292/49523 2368/42074
 No abdominal obesity & Overweight (23–< 25 kg/m2) 1548/37389 0.95 (0.89–1.01) 1427/23721 1.07 (1.00–1.14)
 No abdominal obesity & Obesity (≥25 kg/m2) 1046/24029 1.04 (0.96–1.12) 986/14441 1.21 (1.12–1.30)
 Abdominal obesity * & Underweight/Normal (< 23 kg/m2) 50/842 1.08 (0.82–1.43) 67/1208 0.90 (0.71–1.15)
 Abdominal obesity * & Overweight (23–< 25 kg/m2) 298/5210 1.15 (1.02–1.29) 256/3694 1.15 (1.01–1.31)
 Abdominal obesity * & Obesity (≥25 kg/m2) 1323/27031 1.09 (1.02–1.17) 1203/16857 1.22 (1.13–1.31)
  1. Subgroup analysis was performed using BMI and waist circumference measured in 2008/2009 excluding subjects with asthma diagnosis before the follow-up period. Separate models were developed for BMI, WC and the combination of BMI and WC after adjusting for age, insurance type, household income, smoking, drinking and physical activity
  2. * Abdominal obesity was defined as waist circumference > 100 cm in men or 95 cm in women