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Table 1 Symptoms of airway irritation reported by questionnaire (at least 1 of 2 symptoms: throat irritation and cough) according to ZnO concentrations and time points. Both symptoms were graded according to severity (not at all (0 score point, not illustrated), barely (1 points), little (2 points), moderate (3 points), strong (4 points), very strong (5 points)). Listed values are sums of both graded symptoms (the maximal value is 10)

From: Airway inflammation after inhalation of nano-sized zinc oxide particles in human volunteers

ZnO-Conc. [mg/m3]

 

0

  

0.5

  

1.0

  

2.0

 

Time points

A

B

C

A

B

C

A

B

C

A

B

C

ID

            

1

   

1

      

2

2

1

  

2

  

2

1

4

1

  

3

  

1

2

1

 

1

2

1

 

4

4

4

            

5

   

2

2

1

 

1

1

2

1

 

6

 

1

  

1

2

 

1

 

1

3

2

7

    

1

4

1

3

 

1

4

8

            

9

1

   

2

4

  

2

   

10

    

1

   

1

   

11

   

1

 

1

     

2

12

            

13

 

1

   

2

  

4

1

2

3

14

            

15

      

2

1

    

16

1

1

1

1

  

1

1

   

3

Sum score

3

3

2

8

9

14

7

7

16

5

11

20

% of max. Sum score (160)

1,9

1,9

1,3

5,0

5,6

8,8

4,4

4,4

10,0

3,1

6,9

12,5

  1. Time points A: before exposure, B: directly after exposure, C: 24 h after beginning of exposure. Hyphens indicate missing values. The maximum value of 160 would be reached if both symptoms are reported by all subjects with highest severity