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Table 2 Results of muscle function and muscle metabolism assessment

From: Size-adjusted muscle power and muscle metabolism in patients with cystic fibrosis are equal to healthy controls – a case control study

 

Patients with CF (n = 20)

Healthy controls (n = 23)

Wingate anaerobic test

 Peak power (Watt)

537 ± 180 (258–860)

727 ± 186 (349–1145) ***

 Mean power (Watt)

378 ± 127 (202–619)

486 ± 126 (226–747) ***

 Power drop (Watt)

12 ± 5 (5–25)

8 ± 4 (2–15) ***

MRI spectroscopy – incremental knee-extension protocol

 Maximal load (kg)

6.8 ± 2.0 (3–11)

8.1 ± 2.0 (5–13) *

 Cross-sectional area M. quadriceps (cm3)

57.7 ± 12.4 (38–79)

62.8 ± 12.7 (27–86)

 pH rest

7.1 ± 0.02 (7.04–7.31)

7.1 ± 0.02 (7.04–7.31)

 pH maximum load

7.08 ± 0.06 (6.99–7.21)

7.08 ± 0.03 (7.02–7.19)

 pH recovery

7.03 ± 0.04 (6.92–7.07)

7.04 ± 0.03 (6.97–7.11)

 Pi/PCr rest

0.15 ± 0.03 (0.11–0.23)

0.15 ± 0.03 (0.11–0.21)

 Pi/PCr maximum load

0.34 ± 0.09 (0.21–0.59)

0.36 ± 0.10 (0.23–0.63)

 Pi/PCr recovery

0.14 ± 0.03 (0.09–0.18)

0.13 ± 0.02 (0.10–0.17)

 Time to exhaustion (min)

41.2 ± 7.8 (27–64)

47.8 ± 8.4 (34–52)

 Mean increment (kg)

0.8 ± 0.3 (0.5–1)

0.8 ± 0.2 (0.5–1)

  1. All parameters are reported as mean ± standard deviation (range); differences between participants with and without CF were calculated using Student’s t-test. Significant data is marked by ***p < 0.001, * p < 0.05