| Controls n = 20 | COPD n = 40 | p-value (t-test) |
---|---|---|---|
Anthropometric parameters | |||
 Gender, M/F | 10/10 | 21/19 | – |
 Age, yrs | 61.3 (2.17) | 61.7 (1.73) | 0.97 |
 Weight, kg | 72 (2.59) | 73 (3.96) | 0.89 |
 BMI, kg.m−2 | 25.4 (0.76) | 26.4 (1.26) | 0.46 |
Pulmonary parameters | |||
 FEV1, L | 3.12 (0.2) | 1.3 (0.11) | < 0.001 |
 FEV1, % pred | 113.9 (3.2) | 49.6 (3.66) | < 0.001 |
 FEV1/FVC | 0.74 (0.46) | 0.5 (0.28) | < 0.001 |
Maximal voluntary and electrically evoked quadriceps torque | |||
 QMVC, Nm | 150.3 (15.7) | 99 (10.4) | < 0.05 |
 QPt, Nm | 43.1 (3.71) | 33.5 (3.32) | < 0.05 |
Voluntary activation parameters | |||
 VAperipheral | 93 (1) | 93.1 (1.32) | 0.94 |
 VAcortical, % | 89.8 (1.02) | 85.7 (3.11) | 0.26 |
Peripheral and spinal parameters | |||
 Mmax amplitude, mV | 3.94 (0.38) | 3.32 (0.5) | 0.36 |
 Mmax lat, ms | 5.7 (0.27) | 6.15 (0.25) | 0.38 |
 Hmax/Mmax | 0.188 (0.027) | 0.26 (0.029) | 0.34 |
 Hmax lat, ms | 16.63 (0.54) | 18.98 (0.59) | < 0.01 |
Corticospinal parameters | |||
 MEP/Mmax | 0.374 (0.021) | 0.34 (0.045) | 0.68 |
 CMCT, ms | 20.3 (0.56) | 20.2 (0.54) | 0.59 |
 CSP, ms | 75.6 (7.2) | 103 (4.43) | < 0.001 |