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Table 2 Characteristics of controls and patients with (COPDMW) or without (COPDNoMW) muscle weakness

From: Specific motor cortex hypoexcitability and hypoactivation in COPD patients with peripheral muscle weakness

 Controls (a)COPDNoMW (b)COPDMW (c)ANOVA p-valuep-value
a vs b
p-value
a vs c
p-value
b vs c
Gender, M/F10/1011/710/12
Age, yrs61.3 (2.17)60.8 (2.19)62.4 (1.34)0.84
Weight, kg72 (2.59)75.3 (3.42)71.1 (3.94)0.67
BMI, kg.m−225.4 (0.76)27.3 (1.18)25.8 (1.41)0.53
FEV1, L3.12 (0.2)1.34 (0.14)1.23 (0.09)< 0.001< 0.001< 0.0010.62
FEV1, % pred113.9 (3.2)50.5 (4.21)47.4 (3.18)< 0.001< 0.001< 0.0010.53
FEV1/FVC0.74 (0.11)0.51 (0.32)0.49 (0.27)< 0.001< 0.001< 0.0010.53
PaO2, mmHg72.2 (2.07)65.4 (1.55)< 0.01*
PaCO2, mmHg40.1 (1.59)40.1 (1.1)0.99*
Smoking history (pack-years)7.3 (12.5)38.9 (26.9)45.5 (24)< 0.001< 0.001< 0.0010.39
Number of comorbidities2 (1.2)2.2 (1.1)0.63*
  1. BMI Body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, PaO2 arterial oxygen tension, PaCO2 arterial carbon dioxide tension. Data are mean and SE