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Table 2 Characteristics of controls and patients with (COPDMW) or without (COPDNoMW) muscle weakness

From: Specific motor cortex hypoexcitability and hypoactivation in COPD patients with peripheral muscle weakness

 

Controls (a)

COPDNoMW (b)

COPDMW (c)

ANOVA p-value

p-value

a vs b

p-value

a vs c

p-value

b vs c

Gender, M/F

10/10

11/7

10/12

–

–

–

–

Age, yrs

61.3 (2.17)

60.8 (2.19)

62.4 (1.34)

0.84

–

–

–

Weight, kg

72 (2.59)

75.3 (3.42)

71.1 (3.94)

0.67

–

–

–

BMI, kg.m−2

25.4 (0.76)

27.3 (1.18)

25.8 (1.41)

0.53

–

–

–

FEV1, L

3.12 (0.2)

1.34 (0.14)

1.23 (0.09)

< 0.001

< 0.001

< 0.001

0.62

FEV1, % pred

113.9 (3.2)

50.5 (4.21)

47.4 (3.18)

< 0.001

< 0.001

< 0.001

0.53

FEV1/FVC

0.74 (0.11)

0.51 (0.32)

0.49 (0.27)

< 0.001

< 0.001

< 0.001

0.53

PaO2, mmHg

–

72.2 (2.07)

65.4 (1.55)

–

–

–

< 0.01*

PaCO2, mmHg

–

40.1 (1.59)

40.1 (1.1)

–

–

–

0.99*

Smoking history (pack-years)

7.3 (12.5)

38.9 (26.9)

45.5 (24)

< 0.001

< 0.001

< 0.001

0.39

Number of comorbidities

–

2 (1.2)

2.2 (1.1)

–

–

–

0.63*

  1. BMI Body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, PaO2 arterial oxygen tension, PaCO2 arterial carbon dioxide tension. Data are mean and SE