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Table 3 Muscle and corticospinal excitability assessment

From: Specific motor cortex hypoexcitability and hypoactivation in COPD patients with peripheral muscle weakness

 Controls
(a)
COPDNoMW
(b)
COPDMW
(c)
ANOVA p-valuep-value
a vs b
p-value
a vs c
p-value
b vs c
Muscle and spinal parameters
 Mmax amplitude, mV3.94 (0.38)2.96 (0.3)3.58 (0.55)0.36
 Mmax lat, ms5.7 (0.27)6.21 (0.26)6.11 (0.27)0.38
 Hmax/Mmax0.188 (0.027)0.25 (0.041)0.265 (0.02)0.25
 Hmax lat, ms16.63 (0.54)18.86 (0.62)19.17 (0.51)< 0.05< 0.05< 0.050.77
Corticospinal parameters
 MEP/Mmax0.374 (0.021)0.464 (0.056)0.235 (0.019)< 0.010.22< 0.01< 0.05
 CMCT, ms20.3 (0.56)19.3 (0.45)20.8 (0.55)0.33
 SP, ms75.6 (7.2)108.3 (4.55)98.3 (3.79)< 0.01< 0.01< 0.050.31
  1. Mmax amplitude amplitude of the maximal M-wave, Mmax lat latency of the maximal M-wave, Hmax/Mmax amplitude of the maximal H-wave normalized with respect to the maximal M-wave, Hmax lat latency of the maximal H-wave minus the latency of the maximal M-wave, MEP/Mmax amplitude of the maximal motor evoked potential normalized with respect to the maximal M-wave amplitude, CMCT central motor conduction time, SP silent period duration. Data are mean and SE