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Table 3 Muscle and corticospinal excitability assessment

From: Specific motor cortex hypoexcitability and hypoactivation in COPD patients with peripheral muscle weakness

 

Controls

(a)

COPDNoMW

(b)

COPDMW

(c)

ANOVA p-value

p-value

a vs b

p-value

a vs c

p-value

b vs c

Muscle and spinal parameters

 Mmax amplitude, mV

3.94 (0.38)

2.96 (0.3)

3.58 (0.55)

0.36

–

–

–

 Mmax lat, ms

5.7 (0.27)

6.21 (0.26)

6.11 (0.27)

0.38

–

–

–

 Hmax/Mmax

0.188 (0.027)

0.25 (0.041)

0.265 (0.02)

0.25

–

–

–

 Hmax lat, ms

16.63 (0.54)

18.86 (0.62)

19.17 (0.51)

< 0.05

< 0.05

< 0.05

0.77

Corticospinal parameters

 MEP/Mmax

0.374 (0.021)

0.464 (0.056)

0.235 (0.019)

< 0.01

0.22

< 0.01

< 0.05

 CMCT, ms

20.3 (0.56)

19.3 (0.45)

20.8 (0.55)

0.33

–

–

–

 SP, ms

75.6 (7.2)

108.3 (4.55)

98.3 (3.79)

< 0.01

< 0.01

< 0.05

0.31

  1. Mmax amplitude amplitude of the maximal M-wave, Mmax lat latency of the maximal M-wave, Hmax/Mmax amplitude of the maximal H-wave normalized with respect to the maximal M-wave, Hmax lat latency of the maximal H-wave minus the latency of the maximal M-wave, MEP/Mmax amplitude of the maximal motor evoked potential normalized with respect to the maximal M-wave amplitude, CMCT central motor conduction time, SP silent period duration. Data are mean and SE