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Table 3 Treatment for acute exacerbation in patients with IPF and CPFE-UIP

From: Prognosis of patients with acute exacerbation of combined pulmonary fibrosis and emphysema: a retrospective single-centre study

Treatment

Patients with IPF

(n = 41)

Patients with CPFE

(n = 21)

p-value

Number of patients using corticosteroids

41 (100%)

21 (100%)

Number of patients of using immunosuppressants

19 (46.3%)

4 (19.0%)

0.08

 CY

14 (34.1%)

3 (14.3%)

 

 CyA

4 (9.7%)

2 (9.5%)

 

 TAC

1 (2.4%)

0 (0%)

 

Number of patients receiving respiratory care

  

0.927

 IPPV

8 (19.5%)

3 (14.3%)

 

 NPPV

13 (31.7%)

7 (33.3%)

 HFT

3 (7.3%)

1 (4.8%)

 Only O2

17 (41.5%)

10 (47.6%)

Duration of positive-pressure ventilation (days)

9.5 (3.75–39.25) (n = 20)

5(3.25–7.75) (n = 10)

0.628

ICU stay (days)

10 (4–17.) (n = 13)

4.5 (3.25–8) (n = 6)

0.122

  1. Note: Most invasive respiratory management methods are listed
  2. The data are expressed as the number (percentage) or as the median (interquartile range)
  3. CPFE combined pulmonary fibrosis and emphysema, CY cyclophosphamide, CyA cyclosporine, HFT high-flow therapy, ICU intensive care unit, IPF idiopathic pulmonary fibrosis, IPPV invasive positive-pressure ventilation, NPPV noninvasive positive-pressure ventilation, O2 oxygen, TAC tacrolimus