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Table 2 Stratified results for different empirical prescribing. Unadjusted analysis

From: Empirical prescribing of penicillin G/V reduces risk of readmission of hospitalized patients with community-acquired pneumonia in Norway: a retrospective observational study

 Monotherapy penicillin G/V (n = 335)Combination penicillin G and gentamicin (n = 149)Other antibiotics (n = 167)p-value*
n (%)n (%)n (%)
Age, years
 Mean72.870.870.40.29
 Gender, female150 (44.8)67 (45.0)86 (51.5)0.33
Comorbidities
 COPD94 (28.1)44 (29.5)67 (40.1)0.02
 Heart failure73 (21.8)26 (17.5)41 (24.6)0.30
 Diabetes mellitus I or II50 (14.9)13 (8.7)22 (13.2)0.17
Nursing home resident27 (8.1)22 (14.8)21 (12.6)0.06
Penicillin allergy8 (2.4)2 (1.3)60 (35.9)0.00
CRB-65   0.11
 057 (17.0)23 (15.4)30 (18.0) 
 1127 (37.9)38 (25.5)60 (35.9) 
 287 (26.0)46 (30.9)46 (27.5) 
 315 (4.5)17 (11.4)11 (6.6) 
 42 (0.6)2 (1.3)2 (1.2) 
 Missing data47 (14.0)23 (15.4)18 (10.8) 
Antibiotic use pre-hospitalization64 (19.1)40 (26.9)67 (40.1)0.00
Treatment amended within 3 days56 (16.7)25 (16.8)25 (15.0)0.87
IV treatment duration, mean (days)3.44.14.10.01
Total treatment duration, mean (days)11.412.311.30.04
Clinical outcomes
 30-day readmission38 (11.6)19 (13.4)33 (20.8)0.02
 Length of stay (mean)5.15.85.00.20
 30-day mortality20 (6.0)11 (7.4)13 (7.8)0.70
  1. CRB-65 Confusion, respiration, blood pressure and age ≥ 65y, COPD Chronic obstructive pulmonary disease, IV intravenous
  2. *Categorical data analyzed using Pearson’s χ2-test and continuous data using ANOVA test