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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma

Fig. 3

MiR-449b-5p targeted PSMG3-AS1 to downregulate its expression. The interaction between miR-449b-5p and PSMG3-AS1 was predicted using IntaRNA 2.0 (a). H522 and H23 cells were transfected with miR-449b-5p mimic, PSMG3-AS1 expression vector, or PSMG3-AS1, followed by the confirmation of miR-449b-5p and PSMG3-AS1 overexpression as well as PSMG3-AS1 siRNA silencing by RT-qPCR at 48 h post-transfection (b). The effects of overexpression of miR-449b-5p on PSMG3-AS1 (c) and the effects of overexpression of and silencing of PSMG3-AS1 on miR-449b-5p (d) were also analyzed by RT-qPCR at 48 h post-transfection. All experiments were repeated 3 times and mean values were presented and compared. *, p < 0.05

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