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Table 1 Baseline characteristics of the 17 patients at Burkholderia primary colonisation

From: Management of initial colonisations with Burkholderia species in France, with retrospective analysis in five cystic fibrosis Centres: a pilot study

Patient characteristics (N = 17)Number (percentage) or median value [min-max]
Male gender13 (76.5%)
Age (years)19 [6–34]
CFTR genotype: F508del/F508del3 (17.6%)
 F508del/other or unknown12 (70.6%)
 Other or unknown2 (11.8%)
BMI (Z-score)−0.76 [−2.81–0.39]
Insulin-dependent diabetes3 (17.6%)
Exocrine pancreatic insufficiency16 (94.1%)
Nutritional support (gastrostomy/enteral tube)1 (5.9%)
Liver cirrhosis1 (5.9%)
ABPA3 (17.6%)
Respiratory function tests
 Median FEV1 (% predicted)83.0 [26–113]
 Median FVC (% predicted)92.0 [36–109]
BCC14 (82.4%)
B. multivorans6 (35.3%)
B. cenocepaciaa4 (23.5%)
B. contaminans1 (5.9%)
B. vietnamiensis1 (5.9%)
B. ambifaria1 (5.9%)
 Unidentified BCCb1 (5.9%)
B. gladioli3 (17.6%)
 Methi-S Staphylococcus aureus7 (41.2%)
 Methi-R Staphylococcus aureus5 (29.4%)
Pseudomonas aeruginosa6 (35.3%)
 Fungi4 (23.5%)
Stenotrophomonas maltophilia3 (17.6%)
 Non-tuberculous Mycobacteria2 (11.8%)
Achromobacter spp.0 (0%)
  1. CFTR Cystic Fibrosis Transmembrane conductance Regulator, BMI Body Mass Index, ABPA Allergic Broncho-Pulmonary Aspergillosis, FEV1 Forced Expiratory Volume in one second, FVC Forced Vital Capacity, BCC Burkholderia cepacia complex, Methi-S Methicillin-Susceptible,Methi-R Methicillin-Resistant
  2. a including 3 cenocepacia IIIA and 1 cenocepacia IIIB subtypes
  3. bon the basis of RecA sequencing results analysed using the Burkholderia cepacia complex MLST Databases website (, this isolate was confirmed as BCC, but could not be assigned to any of the BCC species described so far