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Table 2 Organ involvement and histological evidence indicating subjects with evidence of noncaseating granulomas

From: Clinical characteristics and organ system involvement in sarcoidosis: comparison of the University of Minnesota Cohort with other cohorts

Characteristics

Organ Involvement per WASOG Tool

Histological Evidence

n/187

%

95% CI

n/total

%

Lung

184

98.4

95.4–99.7

158/184

85.9

Skin

27

14.4

9.7–20.3

22/27

81.5

Liver

33

17.6

12.5–23.9

12/33

36.4

Eye

39

20.9

15.3–27.4

5/39

12.8

Spleen

39

20.9

15.3–27.4

2/39

5.1

Salivary Gland

4

2.1

0.6–5.4

1/4

25.0

ENT

4

2.1

0.6–5.4

3/4

75.0

Calcium-VitD

10

5.3

2.6–9.6

0/10a

0.0

Bone-Joint

18b

9.6

5.8–14.8

3/18

16.7

Bone Marrow

6

3.2

1.2–6.9

4/6

66.7

Muscle

2

1.1

0.1–3.8

1/2

50.0

Extra-Thoracic Lymph Node

64

34.2

27.5–41.5

18/64

28.1

Kidney

2

1.1

0.1–3.8

2/2

100.0

Nervous System

14

7.5

4.1–12.2

1/14c

7.1

Cardiac

20

10.7

6.7–16.0

3/20

15.0

Other Organs

9

4.8

2.2–8.9

6/9

66.7

 Testis

3

1.6

0.3–4.6

2/3

66.7

 Large intestine

1

0.5

0.0–2.9

1/1

100.0

 Stomach

2

1.1

0.1–3.8

2/2

100.0

 Thyroid

2

1.1

0.1–3.8

0/2

0.0

 Appendix

1

0.5

0.0–2.9

1/1

100.0

  1. a10 subjects with evidence of calcium stones by stone analysis for calcium-vitD involvement
  2. b4 subjects with arthralgia associated with Lofgren’s syndrome was included for bone-joint involvement
  3. c3 subjects with evidence of small fiber neuropathy by skin biopsy for nervous system involvement