Table 1 Baseline characteristics of patients in the modified intention-to-treat (MITT) population
|  | CTRX (n = 124) | ABPC/SBT (n = 139) | p-value |
|---|---|---|---|
Male/female, n (% male) | 63/61 (51) | 80/59 (58) | 0.32* |
Age, y | 60.6 ± 21.3 | 63.4 ± 18.4 | 0.25 |
Comorbidities | |||
 Cancer | 10 (8) | 14 (10) | 0.67* |
 Hematological malignancy | 2 (2) | 0 (0) | 0.22†|
 Cardiovascular disease | 8 (6) | 14 (10) | 0.37* |
 Chronic lung disease | 23 (19) | 24 (17) | 0.87* |
 Bronchial asthma | 11 (9) | 13 (9) | 1.00* |
 COPD | 7 (6) | 8 (6) | 1.00* |
 Chronic liver disease | 2 (2) | 1 (1) | 0.60†|
 Chronic kidney disease | 3 (2) | 2 (1) | 0.67†|
Pneumonia severity index | 67.8 ± 32.6 | 70.7 ± 27.5 | 0.45 |
 Class I, n (%) | 29 (23) | 24 (17) | 0.71‡ |
 Class II, n (%) | 40 (32) | 47 (34) | |
 Class III, n (%) | 25 (20) | 44 (32) | |
 Class IV, n (%) | 24 (19) | 20 (14) | |
 Class V, n (%) | 6 (5) | 4 (3) | |
Performance status, n (%) | |||
 0 | 108 (87) | 122 (88) | 0.87‡ |
 1 | 11 (9) | 12 (9) | |
 2 | 4 (3) | 2 (1) | |
 3 | 0 (0) | 2 (2) | |
 4 | 1 (1) | 1 (1) | |
Maximum body temperature, °C | |||
 Before treatment | 38.1 ± 0.8 | 38.1 ± 1.0 | 0.89 |
 Day of visit | 38.0 ± 0.8 | 38.0 ± 1.0 | 0.79 |
Systolic blood pressure, mmHg | 127.8 ± 21.5 | 131.4 ± 24.8 | 0.22 |
Diastolic blood pressure, mmHg | 73.0 ± 15.9 | 73.1 ± 13.1 | 0.97 |
Pulse rate, beats/min | 90.3 ± 16.7 | 89.0 ± 14.9 | 0.49 |
Respiration rate, breaths/min (n) | 21.2 ± 4.6 (83 cases) | 22.2 ± 5.5 (99 cases) | 0.18 |
CRP, mg/dL | 10.7 ± 7.2 | 12.9 ± 7.7 | 0.02 |
WBC, ×103/μL | 11.6 ± 5.2 | 11.3 ± 5.6 | 0.60 |
Albumin, g/dL (n) | 3.8 ± 0.5 (123 cases) | 3.7 ± 0.4 (137 cases) | 0.42 |