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Table 2 Lung function parameters after visit 4 versus baseline

From: An 8 week open-label interventional multicenter study to explore the lung clearance index as endpoint for clinical trials in cystic fibrosis patients ≥8 years of age, chronically infected with Pseudomonas aeruginosa

Patient #AgeFEV1 at baseline (% predicted)dLCI in % of baselinedFEV1 in % of baselinedCFU [/g]
11782.629.8%11.0%−17,120
21784.73.8%10.6%
33771.5−42.4%7.2%−224,700
41968.2−24.6%7.0%
519115.5−19.8%4.4%
624109.910,5%2.7%−12,200
73577.8−3.0%2.1%−12,640
83779,56.7%0.9%−40
92244.7−24.1%0.6%20,800
101865.9−4.8%0.0%− 225,600
114161.9−4.6%0.0%− 8800
123051.5−15.6%−1.0%100
13888.9− 6.9%−2.2%732
1443101.1%8.7%−5.1%14,000
153467.9%17.1%−6.9%−10,040
162375.3%4.8%−12.5%29,600
172468.6%36.2%−13.0%
  1. CFU colony forming units, d difference at week 4 versus baseline, FEV1 forced expiratory volume in one second, LCI lung clearance index