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Table 2 Characteristics of the included studies with nonresolving acute respiratory distress syndrome (ARDS) patients undergoing transbronchial lung cryobiopsy (TBLC)

From: Transbronchial lung cryobiopsy may be of value for nonresolving acute respiratory distress syndrome: case series and systematic literature review

Study / year Number of patients Ventilation support Final pathology diagnosis Management changes Complications Survivals
Dincer et al./2018 5 MV 5/5 (2 DAD, 2 OP and 1 IPS) 5/5 None 4/5
Cooley et al./2019 11 MV 9/11 (4DAD, 2COP and 3 others) 8/11 4 pneumothorax, 2 persistent air leak, 1 significant bleeding 6/11
Las Heras et al./2019 4 MV 4/4 (3 DAD and 1 other) 2/4 None NA
Current study 5 MV and ECMO 5/5 (2 DAD and 3 others) 5/5 2 significant bleeding 3/5
Summary 25 23/25 (11/25 DAD) 20/25 4/25 pneumothorax, 3/25 significant bleeding, 2/25 persistent air leak 13/21
  1. MV mechanical ventilation; ECMO extracorporeal membrane oxygenation; DAD diffuse alveolar damage; IPS idiopathic pneumonia syndrome; OP organized pneumonia; COP cryptogenic organizing pneumonia; NA not available