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Table 4 Responsiveness of the HRQL measures to continuous changes in ACT

From: How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?

  

T1-T0

T2-T1

T3-T2

Estimate

Stand. error

p-value

Estimate

Stand. error

p-value

Estimate

Stand. error

p-value

AQLQ

Q0.1

0.03

0.01

0.125

0.08

0.02

< 0.0001

0.13

0.01

< 0.0001

 

Q0.5

0.05

0.01

< 0.0001

0.09

0.01

< 0.0001

0.10

0.01

< 0.0001

 

Q0.9

0.05

0.02

0.003

0.09

0.02

< 0.0001

0.01

0.02

< 0.0001

EQ-5D index

Q0.1

0.003

0.004

0.414

0.009

0.002

< 0.0001

0.014

0.004

0.0002

 

Q0.5

0.005

0.001

0.0005

0.005

0.001

0.0001

0.009

0.002

< 0.0001

 

Q0.9

0.005

0.002

0.03

0.0014

0.001

0.171

0.004

0.001

0.008

VAS

Q0.1

1.12

0.40

0.005

1.65

0.31

< 0.0001

1.74

0.35

< 0.0001

 

Q0.5

1.00

0.24

< 0.0001

1.1

0.23

< 0.0001

1.37

0.25

< 0.0001

 

Q0.9

1.08

0.34

0.002

0.68

0.24

0.006

1.13

0.27

< 0.0001

  1. All results are adjusted for group (intervention vs. control), age, sex, smoking status, BMI, employed (yes/no), and HRQL at T0, T1, or T2 respectively. Abbreviations: Stand. error: standard error, ACT: Asthma Control Test, AQLQ: Asthma Quality of Life Questionnaire, VAS: Visual Analog Scale