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Table 4 Predictors of clinical improvement with IDM in the control group (24-months follow-up): Logistic regression analyses

From: Exploring characteristics of COPD patients with clinical improvement after integrated disease management or usual care: post-hoc analysis of the RECODE study

   Univariable analyses
(N = 343–363)
Multivariable analysis
(N = 354)
Predictor Value Odds ratio
(95% CI)
p-value Odds ratio
(95% CI)
p-value
Socio-demographic factors
 Gender Female vs Male 1.70 (0.96–3.03) 0.07   
 Age Each year 0.98 (0.95–1.00) 0.10   
 Living alone Yes vs No 0.82 (0.44–1.52) 0.53   
 Low education Yes vs No 0.99 (0.54–1.81) 0.98   
 Employment Yes vs No 0.99 (0.53–1.88) 0.99   
Lung function and symptoms
 FEV1% predicted Each % predicted 1.01 (1.00–1.03) 0.17   
 Dyspnea - MRC score > 2 Yes vs No 1.54 (0.84–2.82) 0.16   
 Exacerbation frequency of previous year Each exacerbation 1.24 (0.94–1.65) 0.13   
Co-morbidity
 Major cardiovascular disease Yes vs No 2.12 (1.08–4.15) 0.03 1.86 (0.81–4.26) 0.14
 Hypertension Yes vs No 2.16 (1.21–3.86) 0.01 2.00 (0.98–4.08) 0.06
 Diabetes Yes vs No 1.49 (0.71–3.11) 0.29   
 Depression Yes vs No 2.74 (1.26–5.96) 0.01 2.60 (1.06–6.38) 0.04
 Charlson co-morbidity index Each point 1.42 (1.14–1.75) 0.001 1.07 (0.77–1.47) 0.70
Lifestyle, illness behaviour and knowledge
 Current smoker Yes vs No 1.05 (0.58–1.91) 0.88   
 Physical activity (in MET) Each minute 1.00 (1.00–1.00) 0.52   
 Self-management Taking initiatives - each point 1.00 (0.98–1.02) 0.98   
Investment behavior - each point 1.01 (0.99–1.02) 0.62   
Self-efficacy - each point 0.99 (0.97–1.01) 0.33   
  1. Values are presented as odds ratios (95% confidence interval [CI]). Odds ratio > 1 indicates a greater likelihood of clinical improvement with IDM
  2. Multivariable model Cox & Snell R2 = 0.05, Nagelkerke R2 = 0.08
  3. IDM Integrated Disease Management, FEV1 Forced Expiratory Volume in 1 s, post-bronchodilator, predicted according to age and height, MRC Medical Research Council Dyspnea Scale, MET Metabolic Equivalent Time