Skip to main content

Table 1 Major variables used in the model to analyze the cost effectiveness of full chest CT vs conventional calcium score CT (CTCS)

From: Conventional Computed Tomographic Calcium Scoring vs full chest CTCS for lung cancer screening: a cost-effectiveness analysis

Possibilities Base Case Range Reference
Percentage of patients with IPNs on CTCS 11.25% N/A [3]
Percentage of patients with MPNs on CTCS 11.25% 11.25–14.40% [3,4,5]
Malignancy rate of IPNs 3.67% N/A [3]
Malignancy rate of MPNs 3.67% 3.67–5.5% [3]
Percentage of IPNs had invasive diagnostic procedure 6.1% N/A [8]
Percentage of IPNs followed with imaging only 93.9% N/A [8]
Any complications caused by invasive diagnostic procedure 23.9% N/A [8]
Major complications after invasive diagnostic procedure 8.1% N/A [8]
Mortality caused by invasive diagnostic procedure 1.5% n/a [8]
Lifetime cancer recurrence rate 33% n/a [10]
Utility Base Case Range Reference
Baseline utility 0.845 0.838–0.854 [3, 11,12,13]
After lung cancer diagnosis 0.62 0.31–0.83 [3, 11,12,13]
Major complication after invasive procedure 0.5 0.4–0.7 [3, 11, 12]
Minor complication after invasive procedure 0.7 n/a [3, 11, 12]
Cost (in 2018 dollar value) Base Case ($) Range ($) Reference
CTCS 382 156–467 [3]
Invasive procedure 12,321 638–18,970 [11, 12, 14]
Imaging follow-up 954 n/a [11, 12, 14]
Treating major complications 6524 3262 – 19,678 [11, 12, 14]
Treating minor complications 622 311–933 [11, 12, 14]
Cancer treatment 12,217 6109 – 32,304 [11, 12, 14]