Skip to main content

Table 2 Pulmonary function tests, 6-min walk distance and pulmonary artery systolic pressure estimated by echocardiography at the entry date and associations with case status (death)

From: Clinical characteristics and outcomes in adult cystic fibrosis patients with severe lung disease in Porto Alegre, southern Brazil

  All Death Survival Transplant HR (95% CI) p-values
Subjects (n) 39 20 (51.3) 3 (7.7) 16 (41.0)   
FVC (% predicted) 40.5 ± 10.3 42.6 ± 12.9 35.7 ± 4.1 38.9 ± 8.4 1.00 (0.96–1.05) 0.837
FEV1(% predicted) 24.4 ± 3.9 24.3 ± 4.2 23.3 ± 4.6 24.8 ± 3.7 0.95 (0.84–1.07) 0.362
FEV1/FVC (%) 54.7 ± 9.4 53.6 ± 10.5 55.4 ± 3.5 55.9 ± 8.9 0.98 (0.93–1.04) 0.507
SpO2(%) 91.6 ± 4.3 92.7 ± 3.3 87.3 ± 4.5 91.2 ± 5.1 1.03 (0.91–1.2) 0.629
6-MWT (m) 479.9 ± 104.8 481.7 ± 115.3 514.0 ± 51.9 471.6 ± 103.9 0.99 (0.99–1.00) 0.840
PASP ≥ 35 mmHg (yes) 15 (38.5) 6 (30.0) 1 (33.3) 8 (50.0) 2.17 (0.83–5.72) 0.116
  1. Data are presented as n (%) or median ± standard deviation. Hazard ratios (HRs) were derived from Cox regression models. CI confidence interval, FVC forced vital capacity, FEV1 forced expiratory volume in the first second, SpO2 room air saturation of peripheral oxygen (evaluated by a non-invasive pulse oximeter), 6-MWd 6-min walk distance, PASP pulmonary artery systolic pressure