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Table 1 Clinical characteristic of the DM-ILD patients and healthy controls

From: Serum levels of interleukins and S100A8/A9 correlate with clinical severity in patients with dermatomyositis-associated interstitial lung disease

Variables Healthy Controls (n = 30) DM without ILD (n = 14) DM-ILD (n = 40)
Age at onset (years), mean ± SD 45.4 ± 10.3 52.6 ± 19.9 50.1 ± 13.3
Gender (female/male) 19/11 11/3 27/13
Subtype of DM (DM/CADM)   12/2 18/22
Subtype of ILD
 A/SIP in all    17
 CIP in all    13
Pulmonary function tests
 HRCT score    144.5 ± 37.21
 %FVC (%)   84.2 ± 14.6 67.2 ± 19.6
 %DLCO (%)   52.0 ± 26.3 37.4 ± 18.5
Laboratory findings
 CRP (mg/dL) 4.1 ± 3.0 5.9 ± 5.4 13.5 ± 15.5
 ESR (mm/h) 7.7 ± 6.0 20.6 ± 14.4 24.9 ± 21.5
 Ferritin (ng/mL) 172.6 ± 147.5 238.0 ± 244.7 758.7 ± 1036.7
 CK (U/l) 75.3 ± 29.2 100.0 ± 49.3 152.3 ± 204.7
  1. aA/SIP Acute/subacute interstitial pneumonia, CADM clinically amyopathic dermatomyositis, CIP Chronic interstitial pneumonia, CK creatine kinase, CRP C-reactive protein, DLCO% % diffusing capacity of the lungs for carbon monoxide, DM dermatomyositis, ESR erythrocyte sedimentation rate, FVC% % forced vital capacity, HRCT high-resolution computed tomography, ILD interstitial lung disease