From: Do-not-resuscitate orders in patients with community-acquired pneumonia: a retrospective study
Early DNR order n = 107 | Late DNR order n = 70 | p-value | |
---|---|---|---|
Age, median (IQR) | 85 (76–89) | 79 (72–85) | 0.001 |
Sex, male | 46% (49) | 51% (36) | 0.46 |
Nursing home | 53% (56) | 23% (16) | < 0.001 |
Comorbidities | |||
COPD | 22% (23) | 27% (19) | 0.43 |
Oher chronic pulmonary disease | 6% (6) | 7% (5) | 0.68 |
Malignancy | 11% (12) | 9% (6) | 0.57 |
Chronic heart disease | 38% (41) | 23% (16) | 0.03 |
Chronic neurological disease | 33% (35) | 23% (16) | 0.16 |
Diabetes | 7% (8) | 13% (9) | 0.24 |
Chronic liver disease | 0 | 4% (3) | 0.03 |
Chronic kidney disease | 3% (3) | 1% (1) | 0.55 |
Number of comorbidities | |||
None | 25% (26) | 31% (22) | 0.99 |
One | 40% (42) | 41% (29) | 1.00 |
More than one | 35% (37) | 27% (19) | 0.78 |
Severity | |||
CURB-65 0–1 | 11% (9) | 22% (13) | 0.46 |
CURB-65 2 | 31% (26) | 40% (23) | 0.78 |
CURB-65 3–5 | 59% (50) | 38% (22) | 0.04 |
ICU | 20% (22) | 36% (25) | 0.03 |
Intubation | 4% (4) | 26% (17) | < 0.001 |
Antibiotic treatmenta | |||
Monotherapy penicillinb | 31% (33) | 30% (21) | 0.91 |
Monotherapy other betalactam | 33% (35) | 40% (28) | 0.32 |
Combination therapy | 26% (28) | 21% (15) | 0.47 |
Other | 10% (11) | 9% (6) | 0.71 |
Mortality | |||
30-day | 57% (61) | 69% (48) | 0.12 |
90-day | 72% (77) | 80% (56) | 0.23 |
180-day | 77% (82) | 87% (61) | 0.08 |