Table 2 Physiological values and levels of inflammatory cytokines during the experiment

Temp (°C)

Prot-V

37.4 ± 1.1

37.9 ± 1.3

37.8 ± 1.3

Control

37.6 ± 1.3

37.9 ± 1.5

37.9 ± 1.6

MAP (mmHg)

Prot-V

91 ± 11

76 ± 23

63 ± 13

Control

92 ± 9

90 ± 19

71 ± 14

MPAP (mmHg)

Prot-V

28 ± 9

40 ± 5

35 ± 7

Control

25 ± 8

38 ± 4

35 ± 7

CI (L x min^− 1x m^− 2)

Prot-V

2.8 ± 0.5

1.8 ± 0.4

2.0 ± 0.5

Control

2.6 ± 0.5

2.3 ± 0.4

2.2 ± 0.5

Lactate (mmol x L⁻¹)

Prot-V

2.0 ± 0.8

2.6 ± 1.4

2.0 ± 1.0

Control

2.2 ± 1.0

2.7 ± 1.0

2.5 ± 1.0

LVSWI (gm x m⁻² × beat)

Prot-V

33 ± 9

16 ± 10

13 ± 5

Control

32 ± 8

21 ± 7

15 ± 6

Diuresis (mL x h⁻¹)

Prot-V

73 (34–190)

25 (15–42)

15 (10–20)

Control

43 (0–110)

85 (33–110)

11 (4–15)

PaO2/FiO2 (mmHg)

Prot-V

478 ± 61

381 ± 107

368 ± 159

Control

473 ± 70

274 ± 100

219 ± 88

Trc (10⁹x L⁻¹)

Prot-V

388 ± 104

281 ± 107

258 ± 100

Control

389 ± 93

280 ± 68

255 ± 93

PEEP (cmH₂O)

Prot-V

5.1 ± 0.2

10.2 ± 0.4

10.1 ± 0.4

Control

5.0 ± 0

5.0 ± 0

5.0 ± 0

P peak (cmH₂O)

Prot-V

20 ± 4

25 ± 5

26 ± 5

Control

20 ± 4

24 ± 3

25 ± 3

RR (min⁻¹)

Prot-V

31 ± 15

47 ± 11

49 ± 13

Control

20 ± 5

22 ± 3

23 ± 5

VE (L x min⁻¹)

Prot-V

5.8 ± 1.8

7.0 ± 1.8

7.5 ± 1.9

Control

5.3 ± 1.4

5.8 ± 1.1

6.1 ± 1.2

PaCO2 (kPa)

Prot-V

5.2 ± 0.5

5.6 ± 0.6

5.5 ± 0.5

Control

5.1 ± 0.4

5.5 ± 0.7

5.6 ± 0.6

Leukocytes (10⁹x L⁻¹)

Prot-V

9 ± 4

10 ± 8

8 ± 5

Control

10 ± 5

8 ± 5

7 ± 4

Neutrophils (10⁹x L⁻¹)

Prot-V

3 ± 3

6 ± 8

5 ± 5

Control

4 ± 4

4 ± 4

4 ± 3

TNF (log₁₀ng x L⁻¹)

Prot-V

3.3 ± 0.6

3.3 ± 0.2

3.0 ± 0.2

Control

3.1 ± 0.7

3.6 ± 0.5

3.2 ± 0.4

IL6 (log₁₀ng x L⁻¹)

Prot-V

1.8 ± 0.4

2.4 ± 0.3

3.1 ± 0.2

Control

1.7 ± 0.5

2.6 ± 0.5

3.2 ± 0.3

IL10 (log₁₀ng x L⁻¹)

Prot-V

1.9 ± 0.5

1.6 ± 0.2

1.6 ± 0.2

Control

2.0 ± 0.5

1.8 ± 0.4

1.8 ± 0.5