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Table 2 Physiological values and levels of inflammatory cytokines during the experiment

From: Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis

Variable Group 0 h 3 h 5 h
Temp (°C) Prot-V 37.4 ± 1.1 37.9 ± 1.3 37.8 ± 1.3
Control 37.6 ± 1.3 37.9 ± 1.5 37.9 ± 1.6
MAP (mmHg) Prot-V 91 ± 11 76 ± 23 63 ± 13
Control 92 ± 9 90 ± 19 71 ± 14
MPAP (mmHg) Prot-V 28 ± 9 40 ± 5 35 ± 7
Control 25 ± 8 38 ± 4 35 ± 7
CI (L x min− 1x m− 2) Prot-V 2.8 ± 0.5 1.8 ± 0.4 2.0 ± 0.5
Control 2.6 ± 0.5 2.3 ± 0.4 2.2 ± 0.5
Lactate (mmol x L−1) Prot-V 2.0 ± 0.8 2.6 ± 1.4 2.0 ± 1.0
Control 2.2 ± 1.0 2.7 ± 1.0 2.5 ± 1.0
LVSWI (gm x m−2 × beat) Prot-V 33 ± 9 16 ± 10 13 ± 5
Control 32 ± 8 21 ± 7 15 ± 6
Diuresis (mL x h−1) Prot-V 73 (34–190) 25 (15–42) 15 (10–20)
Control 43 (0–110) 85 (33–110) 11 (4–15)
PaO2/FiO2 (mmHg) Prot-V 478 ± 61 381 ± 107 368 ± 159
Control 473 ± 70 274 ± 100 219 ± 88
Trc (109x L−1) Prot-V 388 ± 104 281 ± 107 258 ± 100
Control 389 ± 93 280 ± 68 255 ± 93
PEEP (cmH2O) Prot-V 5.1 ± 0.2 10.2 ± 0.4 10.1 ± 0.4
Control 5.0 ± 0 5.0 ± 0 5.0 ± 0
P peak (cmH2O) Prot-V 20 ± 4 25 ± 5 26 ± 5
Control 20 ± 4 24 ± 3 25 ± 3
RR (min−1) Prot-V 31 ± 15 47 ± 11 49 ± 13
Control 20 ± 5 22 ± 3 23 ± 5
VE (L x min−1) Prot-V 5.8 ± 1.8 7.0 ± 1.8 7.5 ± 1.9
Control 5.3 ± 1.4 5.8 ± 1.1 6.1 ± 1.2
PaCO2 (kPa) Prot-V 5.2 ± 0.5 5.6 ± 0.6 5.5 ± 0.5
Control 5.1 ± 0.4 5.5 ± 0.7 5.6 ± 0.6
Leukocytes (109x L−1) Prot-V 9 ± 4 10 ± 8 8 ± 5
Control 10 ± 5 8 ± 5 7 ± 4
Neutrophils (109x L−1) Prot-V 3 ± 3 6 ± 8 5 ± 5
Control 4 ± 4 4 ± 4 4 ± 3
TNF (log10ng x L−1) Prot-V 3.3 ± 0.6 3.3 ± 0.2 3.0 ± 0.2
Control 3.1 ± 0.7 3.6 ± 0.5 3.2 ± 0.4
IL6 (log10ng x L−1) Prot-V 1.8 ± 0.4 2.4 ± 0.3 3.1 ± 0.2
Control 1.7 ± 0.5 2.6 ± 0.5 3.2 ± 0.3
IL10 (log10ng x L−1) Prot-V 1.9 ± 0.5 1.6 ± 0.2 1.6 ± 0.2
Control 2.0 ± 0.5 1.8 ± 0.4 1.8 ± 0.5
  1. Group Prot-V (n = 20) and group Control (n = 10). Values are given as mean ± SD and median (interquartile range). MAP-mean arterial blood pressure, MPAP-mean pulmonary arterial pressure, CI-cardiac index, Lactate-arterial lactate, LVSWI-left ventricular stroke work index, PaO2/FiO2-ratio of arterial partial pressure of oxygen to fraction of inspired oxygen, P peak-peak intratracheal pressure, RR-respiratory rate, VE-expired minute ventilation, PaCO2-arterial partial pressure of carbon dioxide, TNF-α- arterial tumor necrosis factor alpha, IL-6-arterial interleukin 6, IL-10-arterial interleukin 10