TY - JOUR AU - Humbert, M. AU - Guignabert, C. AU - Bonnet, S. PY - 2019 DA - 2019// TI - Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives JO - Eur Respir J VL - 53 ID - Humbert2019 ER - TY - JOUR AU - Galie, N. AU - Humbert, M. AU - Vachiery, J. L. AU - Gibbs, S. AU - Lang, I. AU - Torbicki, A. AU - Simonneau, G. AU - Peacock, A. AU - Vonk Noordegraaf, A. AU - Beghetti, M. PY - 2016 DA - 2016// TI - 2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) JO - Eur Heart J VL - 37 ID - Galie2016 ER - TY - JOUR AU - D'Alonzo, G. E. AU - Barst, R. J. AU - Ayres, S. M. AU - Bergofsky, E. H. AU - Brundage, B. H. AU - Detre, K. M. AU - Fishman, A. P. AU - Goldring, R. M. AU - Groves, B. M. AU - Kernis, J. T. PY - 1991 DA - 1991// TI - Survival in patients with primary pulmonary hypertension. Results from a national prospective registry JO - Ann Intern Med VL - 115 ID - D'Alonzo1991 ER - TY - JOUR AU - Farber, H. W. AU - Miller, D. P. AU - Poms, A. D. AU - Badesch, D. B. AU - Frost, A. E. AU - Muros-Le Rouzic, E. AU - Romero, A. J. AU - Benton, W. W. AU - Elliott, C. G. AU - McGoon, M. D. PY - 2015 DA - 2015// TI - Five-year outcomes of patients enrolled in the REVEAL registry JO - Chest VL - 148 ID - Farber2015 ER - TY - BOOK PY - 2018 DA - 2018// TI - EU/3/04/234 ID - ref5 ER - TY - JOUR AU - Galiè, N. AU - Channick, R. N. AU - Frantz, R. P. PY - 2019 DA - 2019// TI - Risk stratification and medical therapy of pulmonary arterial hypertension JO - Eur Respir J VL - 53 ID - Galiè2019 ER - TY - JOUR AU - Jansen, J. P. AU - Fleurence, R. AU - Devine, B. AU - Itzler, R. AU - Barrett, A. AU - Hawkins, N. AU - Lee, K. AU - Boersma, C. AU - Annemans, L. AU - Cappelleri, J. C. PY - 2011 DA - 2011// TI - Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR task force on indirect treatment comparisons good research practices: part 1 JO - Value Health VL - 14 ID - Jansen2011 ER - TY - JOUR AU - Higgins, J. P. AU - Altman, D. G. AU - Gotzsche, P. C. AU - Juni, P. AU - Moher, D. AU - Oxman, A. D. AU - Savovic, J. AU - Schulz, K. F. AU - Weeks, L. AU - Sterne, J. A. PY - 2011 DA - 2011// TI - The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials JO - BMJ (Clin Res Ed) VL - 343 ID - Higgins2011 ER - TY - JOUR AU - Moher, D. AU - Liberati, A. AU - Tetzlaff, J. AU - Altman, D. G. PY - 2009 DA - 2009// TI - Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement JO - PLoS Med VL - 6 ID - Moher2009 ER - TY - BOOK PY - 2013 DA - 2013// TI - Guide to the methods of technology appraisal 2013. National Institute for Health and Care Excellence (NICE) ID - ref10 ER - TY - BOOK PY - 2009 DA - 2009// TI - Systematic reviews: CRD’s guidance for undertaking reviews in health care. Centre for Reviews and Dissemination (CRD) ID - ref11 ER - TY - BOOK PY - 2011 DA - 2011// TI - Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011] the Cochrane Collaboration ID - ref12 ER - TY - CHAP AU - Ades, A. E. AU - Caldwell, D. M. AU - Reken, S. AU - Welton, N. J. AU - Sutton, A. J. AU - Dias, S. PY - 2012 DA - 2012// TI - NICE decision support unit technical support documents BT - Evidence synthesis of treatment efficacy in decision making: a reviewer’s checklist PB - National Institute for Health and Care Excellence (NICE) CY - London ID - Ades2012 ER - TY - JOUR AU - Jansen, J. P. AU - Trikalinos, T. AU - Cappelleri, J. C. AU - Daw, J. AU - Andes, S. AU - Eldessouki, R. AU - Salanti, G. PY - 2014 DA - 2014// TI - Indirect treatment comparison/network meta-analysis study questionnaire to assess relevance and credibility to inform health care decision making: an ISPOR-AMCP-NPC good practice task force report JO - Value Health VL - 17 ID - Jansen2014 ER - TY - JOUR AU - Hutton, B. AU - Salanti, G. AU - Caldwell, D. M. AU - Chaimani, A. AU - Schmid, C. H. AU - Cameron, C. AU - Ioannidis, J. P. AU - Straus, S. AU - Thorlund, K. AU - Jansen, J. P. PY - 2015 DA - 2015// TI - The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations JO - Ann Intern Med VL - 162 ID - Hutton2015 ER - TY - JOUR AU - Guyatt, G. H. AU - Oxman, A. D. AU - Schunemann, H. J. AU - Tugwell, P. AU - Knottnerus, A. PY - 2011 DA - 2011// TI - GRADE guidelines: a new series of articles in the journal of clinical epidemiology JO - J Clin Epidemiol VL - 64 ID - Guyatt2011 ER - TY - JOUR AU - Avouac, J. AU - Wipff, J. AU - Kahan, A. AU - Allanore, Y. PY - 2008 DA - 2008// TI - Effects of oral treatments on exercise capacity in systemic sclerosis related pulmonary arterial hypertension: a meta-analysis of randomised controlled trials JO - Ann Rheum Dis VL - 67 ID - Avouac2008 ER - TY - JOUR AU - Badiani, B. AU - Messori, A. PY - 2016 DA - 2016// TI - Targeted treatments for pulmonary arterial hypertension: interpreting outcomes by network meta-analysis JO - Heart Lung Circ VL - 25 ID - Badiani2016 ER - TY - JOUR AU - Bai, Y. AU - Sun, L. AU - Hu, S. AU - Wei, Y. PY - 2011 DA - 2011// TI - Combination therapy in pulmonary arterial hypertension: a meta-analysis JO - Cardiology VL - 120 ID - Bai2011 ER - TY - JOUR AU - Barnes, H. AU - Brown, Z. AU - Burns, A. AU - Williams, T. PY - 2019 DA - 2019// TI - Phosphodiesterase 5 inhibitors for pulmonary hypertension JO - Cochrane Database Syst Rev VL - 1 ID - Barnes2019 ER - TY - JOUR AU - Biondi-Zoccai, G. AU - D'Ascenzo, F. AU - Cannillo, M. AU - Welton, N. J. AU - Marra, W. G. AU - Omede, P. AU - Libertucci, D. AU - Fusaro, E. AU - Capriolo, M. AU - Perversi, J. PY - 2013 DA - 2013// TI - Choosing the best first line oral drug agent in patients with pulmonary hypertension: evidence from a network meta-analysis JO - Int J Cardiol VL - 168 ID - Biondi-Zoccai2013 ER - TY - JOUR AU - Chen, Y. F. AU - Jowett, S. AU - Barton, P. AU - Malottki, K. AU - Hyde, C. AU - Gibbs, J. S. R. AU - Pepke-Zaba, J. AU - Fry-Smith, A. AU - Roberts, J. AU - Moore, D. PY - 2009 DA - 2009// TI - Clinical and cost-effectiveness of epoprostenol, iloprost, bosentan, sitaxentan and sildenafil for pulmonary arterial hypertension within their licensed indications: a systematic review and economic evaluation JO - Health Technol Assess VL - 13 ID - Chen2009 ER - TY - JOUR AU - Coeytaux, R. R. AU - Schmit, K. M. AU - Kraft, B. D. AU - Kosinski, A. S. AU - Mingo, A. M. AU - Vann, L. M. AU - Gilstrap, D. L. AU - Hargett, C. W. AU - Heidenfelder, B. AU - Dolor, R. J. PY - 2014 DA - 2014// TI - Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension JO - Chest VL - 145 ID - Coeytaux2014 ER - TY - JOUR AU - Dranitsaris, G. AU - Mehta, S. PY - 2009 DA - 2009// TI - Oral therapies for the treatment of pulmonary arterial hypertension: a population-based cost-minimization analysis JO - Appl Health Econ Health Policy VL - 7 ID - Dranitsaris2009 ER - TY - JOUR AU - Duo-Ji, M. M. AU - Long, Z. W. PY - 2017 DA - 2017// TI - Comparative efficacy and acceptability of endothelin receptor antagonists for pulmonary arterial hypertension: a network meta-analysis JO - Int J Cardiol VL - 234 ID - Duo-Ji2017 ER - TY - JOUR AU - Fox, B. D. AU - Shimony, A. AU - Langleben, D. PY - 2011 DA - 2011// TI - Meta-analysis of monotherapy versus combination therapy for pulmonary arterial hypertension JO - Am J Cardiol VL - 108 ID - Fox2011 ER - TY - JOUR AU - Fox, B. D. AU - Shtraichman, O. AU - Langleben, D. AU - Shimony, A. AU - Kramer, M. R. PY - 2016 DA - 2016// TI - Combination therapy for pulmonary arterial hypertension: a systematic review and meta-analysis JO - Can J Cardiol VL - 32 ID - Fox2016 ER - TY - JOUR AU - Gabler, N. B. AU - French, B. AU - Strom, B. L. AU - Palevsky, H. I. AU - Taichman, D. B. AU - Kawut, S. M. AU - Halpern, S. D. PY - 2012 DA - 2012// TI - Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials JO - Circulation VL - 126 ID - Gabler2012 ER - TY - JOUR AU - Galie, N. AU - Manes, A. AU - Negro, L. AU - Palazzini, M. AU - Bacchi-Reggiani, M. L. AU - Branzi, A. PY - 2009 DA - 2009// TI - A meta-analysis of randomized controlled trials in pulmonary arterial hypertension JO - Eur Heart J VL - 30 ID - Galie2009 ER - TY - JOUR AU - Gao, X. F. AU - Zhang, J. J. AU - Jiang, X. M. AU - Ge, Z. AU - Wang, Z. M. AU - Li, B. AU - Mao, W. X. AU - Chen, S. L. PY - 2017 DA - 2017// TI - Targeted drugs for pulmonary arterial hypertension: a network meta-analysis of 32 randomized clinical trials JO - Patient Prefer Adherence VL - 11 ID - Gao2017 ER - TY - JOUR AU - He, B. AU - Zhang, F. AU - Li, X. AU - Tang, C. AU - Lin, G. AU - Du, J. AU - Jin, H. PY - 2010 DA - 2010// TI - Meta-analysis of randomized controlled trials on treatment of pulmonary arterial hypertension JO - Circ J VL - 74 ID - He2010 ER - TY - JOUR AU - Igarashi, A. AU - Inoue, S. AU - Ishii, T. AU - Tsutani, K. AU - Watanabe, H. PY - 2016 DA - 2016// TI - Comparative effectiveness of oral medications for pulmonary arterial hypertension: network meta-analysis JO - Int Heart J VL - 57 ID - Igarashi2016 ER - TY - JOUR AU - Jain, S. AU - Khera, R. AU - Girotra, S. AU - Badesch, D. AU - Wang, Z. AU - Murad, M. H. AU - Blevins, A. AU - Schmidt, G. A. AU - Singh, S. AU - Gerke, A. K. PY - 2017 DA - 2017// TI - Comparative effectiveness of pharmacologic interventions for pulmonary arterial hypertension: a systematic review and network meta-analysis JO - Chest VL - 151 ID - Jain2017 ER - TY - JOUR AU - Khouri, C. AU - Lepelley, M. AU - Roustit, M. AU - Montastruc, F. AU - Humbert, M. AU - Cracowski, J. L. PY - 2018 DA - 2018// TI - Comparative safety of drugs targeting the nitric oxide pathway in pulmonary hypertension: a mixed approach combining a meta-analysis of clinical trials and a disproportionality analysis from the World Health Organization pharmacovigilance database JO - Chest VL - 154 ID - Khouri2018 ER - TY - JOUR AU - Kirtania, L. AU - Maiti, R. AU - Srinivasan, A. AU - Mishra, A. PY - 2019 DA - 2019// TI - Effect of combination therapy of endothelin receptor antagonist and phosphodiesterase-5 inhibitor on clinical outcome and pulmonary haemodynamics in patients with pulmonary arterial hypertension: a meta-analysis JO - Clin Drug Invest VL - 39 ID - Kirtania2019 ER - TY - JOUR AU - Kuwana, M. AU - Watanabe, H. AU - Matsuoka, N. AU - Sugiyama, N. PY - 2013 DA - 2013// TI - Pulmonary arterial hypertension associated with connective tissue disease: meta-analysis of clinical trials JO - BMJ Open VL - 3 (8) (no pagination) ID - Kuwana2013 ER - TY - JOUR AU - Lajoie, A. C. AU - Lauziere, G. AU - Lega, J. C. AU - Lacasse, Y. AU - Martin, S. AU - Simard, S. AU - Bonnet, S. AU - Provencher, S. PY - 2016 DA - 2016// TI - Combination therapy versus monotherapy for pulmonary arterial hypertension: a meta-analysis JO - Lancet Respir Med VL - 4 ID - Lajoie2016 ER - TY - JOUR AU - Lajoie, A. C. AU - Guay, C. A. AU - Lega, J. C. AU - Lauziere, G. AU - Simard, S. AU - Lambert, C. AU - Lacasse, Y. AU - Bonnet, S. AU - Provencher, S. PY - 2018 DA - 2018// TI - Trial duration and risk reduction in combination therapy trials for pulmonary arterial hypertension: a systematic review JO - Chest VL - 153 ID - Lajoie2018 ER - TY - STD TI - Lei Y, Zhang X, Lin H, Feng Y, Wang J, Luo R. The effects of oral treatment for systemic sclerosis related pulmonary arterial hypertension: a systematic review and meta-analysis. Mod Rheumatol. 2020:1–11. ID - ref39 ER - TY - JOUR AU - Li, T. AU - Chen, Y. AU - Zang, W. AU - Geng, N. AU - Ma, S. AU - Li, X. PY - 2013 DA - 2013// TI - Prostacyclin and its analogues in pulmonary artery hypertension: a meta-analysis JO - Curr Med Res Opin VL - 29 ID - Li2013 ER - TY - JOUR AU - Li, X. AU - Li, T. PY - 2020 DA - 2020// TI - Combined methods (formal adjusted indirect comparison, meta-analysis and principal component analysis) comparisons of the safety and efficacy of ambrisentan, bosentan, and sildenafil in the patients with pulmonary arterial hypertension JO - Front Pharmacol VL - 11 ID - Li2020 ER - TY - JOUR AU - Lin, H. AU - Wang, M. AU - Yu, Y. AU - Qin, Z. AU - Zhong, X. AU - Ma, J. AU - Zhao, F. AU - Zhang, X. PY - 2018 DA - 2018// TI - Efficacy and tolerability of pharmacological interventions for pulmonary arterial hypertension: a network meta-analysis JO - Pulm Pharmacol Ther VL - 50 ID - Lin2018 ER - TY - JOUR AU - Liu, H. L. AU - Chen, X. Y. AU - Li, J. R. PY - 2016 DA - 2016// TI - Efficacy and safety of pulmonary arterial hypertension-specific therapy in pulmonary arterial hypertension: a metaanalysis of randomized controlled trials JO - Chest. VL - 150 ID - Liu2016 ER - TY - JOUR AU - Macchia, A. AU - Marchioli, R. AU - Marfisi, R. AU - Scarano, M. AU - Levantesi, G. AU - Tavazzi, L. AU - Tognoni, G. PY - 2007 DA - 2007// TI - A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology JO - Am Heart J VL - 153 ID - Macchia2007 ER - TY - JOUR AU - Macchia, A. AU - Marchioli, R. AU - Tognoni, G. AU - Scarano, M. AU - Marfisi, R. AU - Tavazzi, L. AU - Rich, S. PY - 2010 DA - 2010// TI - Systematic review of trials using vasodilators in pulmonary arterial hypertension: why a new approach is needed JO - Am Heart J VL - 159 ID - Macchia2010 ER - TY - JOUR AU - Pan, Y. AU - Hu, C. AU - Chen, P. H. AU - Gu, Y. H. AU - Qiao, Q. Y. AU - Pan, L. H. AU - Zhou, D. C. AU - Gu, H. F. AU - Fu, S. K. AU - Jin, H. M. PY - 2017 DA - 2017// TI - Association of oral endothelin receptor antagonists with risks of cardiovascular events and mortality: meta-analysis of randomized controlled trials JO - Eur J Clin Pharmacol VL - 73 ID - Pan2017 ER - TY - JOUR AU - Pan, J. AU - Lei, L. AU - Zhao, C. PY - 2018 DA - 2018// TI - Comparison between the efficacy of combination therapy and monotherapy in connective tissue disease associated pulmonary arterial hypertension: a systematic review and meta-analysis JO - Clin Exp Rheumatol VL - 14 ID - Pan2018 ER - TY - STD TI - Paramothayan NS, Lasserson TJ, Wells AU, Walters EH. Prostacyclin for pulmonary hypertension in adults. Cochrane Database Syst Rev (Online). 2009;(2):CD002994. ID - ref48 ER - TY - JOUR AU - Petrovic, M. AU - Locatelli, I. PY - 2020 DA - 2020// TI - A Bayesian network meta-analysis of add-on drug therapies specific for pulmonary arterial hypertension JO - Ann Pharmacother VL - 54 ID - Petrovic2020 ER - TY - JOUR AU - Petrovic, M. AU - Locatelli, I. PY - 2020 DA - 2020// TI - Comparative effectiveness of pulmonary arterial hypertension drugs in treatment-naive patients: a network meta-analysis JO - J Comp Eff Res VL - 9 ID - Petrovic2020 ER - TY - JOUR AU - Ryerson, C. J. AU - Nayar, S. AU - Swiston, J. R. AU - Sin, D. D. PY - 2010 DA - 2010// TI - Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis JO - Respir Res VL - 11 (no pagination) ID - Ryerson2010 ER - TY - JOUR AU - Savarese, G. AU - Paolillo, S. AU - Costanzo, P. AU - D'Amore, C. AU - Cecere, M. AU - Losco, T. AU - Musella, F. AU - Gargiulo, P. AU - Marciano, C. AU - Perrone-Filardi, P. PY - 2012 DA - 2012// TI - Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension?: a meta-analysis of 22 randomized trials JO - J Am Coll Cardiol VL - 60 ID - Savarese2012 ER - TY - JOUR AU - Savarese, G. AU - Musella, F. AU - Losco, T. AU - Marciano, C. AU - Gargiulo, P. AU - Rengo, G. AU - Dellegrottaglie, S. AU - Bossone, E. AU - Leosco, D. PY - 2013 DA - 2013// TI - Haemodynamics, exercise capacity and clinical events in pulmonary arterial hypertension JO - Eur Respir J VL - 42 ID - Savarese2013 ER - TY - JOUR AU - Silva, M. A. AU - Donovan, J. L. AU - Durie, R. AU - Ventura, D. AU - Alspach, R. M. AU - Kanaan, A. O. AU - Njoroge, M. PY - 2017 DA - 2017// TI - A mixed treatment comparison meta-analysis of pharmacotherapeutic monotherapy and placebo for pulmonary artery hypertension JO - Clin Pulm Med VL - 24 ID - Silva2017 ER - TY - JOUR AU - Steele, P. AU - Strange, G. AU - Wlodarczyk, J. AU - Dalton, B. AU - Stewart, S. AU - Gabbay, E. AU - Keogh, A. PY - 2010 DA - 2010// TI - Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy? JO - BMC Cardiovasc Disord VL - 10 ID - Steele2010 ER - TY - JOUR AU - Thom, H. H. AU - Capkun, G. AU - Cerulli, A. AU - Nixon, R. M. AU - Howard, L. S. PY - 2015 DA - 2015// TI - Network meta-analysis combining individual patient and aggregate data from a mixture of study designs with an application to pulmonary arterial hypertension JO - BMC Med Res Methodol VL - 15 ID - Thom2015 ER - TY - STD TI - Tran K, Coyle K, Jabr MF, Coyle D, Boucher M, Mielniczuk L, Swiston JR, Rabb D, Cimon K, Blouin J, Innes M. Drugs for pulmonary arterial hypertension: comparative efficacy, safety, and cost-effectiveness: Canadian Agency for Drugs and Technologies in Health; 2015. ID - ref57 ER - TY - JOUR AU - Vizza, C. D. AU - Badagliacca, R. AU - Messick, C. R. AU - Rao, Y. AU - Nelsen, A. C. AU - Benza, R. L. PY - 2018 DA - 2018// TI - The impact of delayed treatment on 6-minute walk distance test in patients with pulmonary arterial hypertension: a meta-analysis JO - Int J Cardiol VL - 254 ID - Vizza2018 ER - TY - JOUR AU - Wang, S. AU - Yu, M. AU - Zheng, X. AU - Dong, S. PY - 2018 DA - 2018// TI - A Bayesian network meta-analysis on the efficacy and safety of eighteen targeted drugs or drug combinations for pulmonary arterial hypertension JO - Drug Deliv VL - 25 ID - Wang2018 ER - TY - JOUR AU - Wei, A. AU - Gu, Z. AU - Li, J. AU - Liu, X. AU - Wu, X. AU - Han, Y. AU - Pu, J. PY - 2016 DA - 2016// TI - Clinical adverse effects of endothelin receptor antagonists: insights from the meta-analysis of 4894 patients from 24 randomized double-blind placebo-controlled clinical trials JO - J Am Heart Assoc VL - 5 (11) (no pagination) ID - Wei2016 ER - TY - JOUR AU - Xing, X. Q. AU - Han, B. AU - Wu, X. W. AU - Xiao, Y. AU - Wu, S. J. PY - 2011 DA - 2011// TI - Efficacy and safety of prostacyclins therapy in pulmonary arterial hypertension: a meta-analysis JO - Afr J Pharm Pharmacol VL - 5 ID - Xing2011 ER - TY - JOUR AU - Zhang, H. D. AU - Zhang, R. AU - Jiang, X. AU - Sun, K. AU - Wu, D. C. AU - Jing, Z. C. PY - 2015 DA - 2015// TI - Effects of oral treatments on clinical outcomes in pulmonary arterial hypertension: a systematic review and meta-analysis JO - Am Heart J VL - 170 ID - Zhang2015 ER - TY - JOUR AU - Zhang, H. AU - Li, X. AU - Huang, J. AU - Li, H. AU - Su, Z. AU - Wang, J. PY - 2016 DA - 2016// TI - Comparative efficacy and safety of prostacyclin analogs for pulmonary arterial hypertension: a network meta-analysis JO - Medicine VL - 95 ID - Zhang2016 ER - TY - JOUR AU - Zhang, Y. J. AU - Wang, N. AU - Gu, Z. C. AU - Wei, A. H. AU - Cheng, A. N. AU - Fang, S. S. AU - Du, H. L. AU - Wang, L. Z. AU - Zhang, G. Q. PY - 2019 DA - 2019// TI - A network meta-analysis for safety of endothelin receptor antagonists in pulmonary arterial hypertension JO - Cardiovasc Diagn Ther VL - 9 ID - Zhang2019 ER - TY - JOUR AU - Zheng, Y. AU - Xiong, C. M. PY - 2014 DA - 2014// TI - Oral targeted therapies in the treatment of pulmonary arterial hypertension: a meta-analysis of clinical trials JO - Eur Heart J VL - 1 ID - Zheng2014 ER - TY - JOUR AU - Zheng, Y. AU - Yang, T. AU - Chen, G. AU - Hu, E. AU - Gu, Q. AU - Xiong, C. PY - 2014 DA - 2014// TI - Prostanoid therapy for pulmonary arterial hypertension: a meta-analysis of survival outcomes JO - Eur J Clin Pharmacol VL - 70 ID - Zheng2014 ER - TY - JOUR AU - Zheng, Y. G. AU - Ma, H. AU - Chen, L. AU - Jiang, X. M. AU - Zhou, L. AU - Lin, S. AU - Chen, S. L. PY - 2018 DA - 2018// TI - Efficacy and safety of oral targeted therapies in pulmonary arterial hypertension: a meta-analysis of randomized clinical trials JO - Pulm Circ VL - 8 ID - Zheng2018 ER - TY - JOUR AU - Zhu, B. AU - Wang, L. AU - Sun, L. AU - Cao, R. PY - 2012 DA - 2012// TI - Combination therapy improves exercise capacity and reduces risk of clinical worsening in patients with pulmonary arterial hypertension: a meta-analysis JO - J Cardiovasc Pharmacol VL - 60 ID - Zhu2012 ER - TY - STD TI - Liu C, Chen J, Gao Y, Deng B, Liu K. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database Syst Rev. 2013;(2). ID - ref69 ER - TY - JOUR AU - Singh, T. AU - Rohit, M. AU - Grover, A. AU - Malhotra, S. AU - Vijayvergiya, R. PY - 2006 DA - 2006// TI - A randomized, placebo-controlled, double-blind, crossover study to evaluate the efficacy of oral sildenafil therapy in severe pulmonary artery hypertension JO - Am Heart J VL - 151 ID - Singh2006 ER - TY - JOUR AU - Galie, N. AU - Badesch, D. AU - Oudiz, F. AU - Simonneau, G. AU - McGoon, M. AU - Keogh, A. AU - Frost, A. AU - Zwicke, D. AU - Naeije, R. AU - Shapiro, S. PY - 2005 DA - 2005// TI - Ambisentan therapy for pulmonary arterial hypertension JO - J Am Coll Cardiol VL - 46 ID - Galie2005 ER - TY - JOUR AU - Pulido, T. AU - Adzerikho, I. AU - Channick, R. AU - Delcroix, M. AU - Galie, N. AU - Ghofrani, H. AU - Jansa, P. AU - Jing, Z. PY - 2013 DA - 2013// TI - Macitentan and morbidity and mortality in pulmonary arterial hypertension JO - N Engl J Med VL - 369 ID - Pulido2013 ER - TY - JOUR AU - Galie, N. AU - Barbera, J. AU - Frost, A. AU - Ghofrani, H. AU - Hoeper, M. AU - McLaughlin, A. AU - Peacock, A. AU - Simonneau, G. PY - 2015 DA - 2015// TI - Initial use of Ambrisentan plus Tadalafil in pulmonary arterial hypertension JO - N Engl J Med VL - 373 ID - Galie2015 ER - TY - JOUR AU - Sitbon, O. AU - Channick, R. AU - Chin, K. M. AU - Frey, A. AU - Gaine, S. AU - Galiè, N. AU - Ghofrani, H. -. A. AU - Hoeper, M. M. AU - Lang, I. M. AU - Preiss, R. PY - 2015 DA - 2015// TI - Selexipag for the treatment of pulmonary arterial hypertension JO - N Engl J Med VL - 373 ID - Sitbon2015 ER - TY - JOUR AU - Cipriani, A. AU - Higgins, J. P. AU - Geddes, J. R. AU - Salanti, G. PY - 2013 DA - 2013// TI - Conceptual and technical challenges in network meta-analysis JO - Ann Intern Med VL - 159 ID - Cipriani2013 ER - TY - JOUR AU - Salanti, G. AU - Giovane, C. AU - Chaimani, A. AU - Caldwell, D. M. AU - Higgins, J. P. PY - 2014 DA - 2014// TI - Evaluating the quality of evidence from a network meta-analysis JO - PLoS One VL - 9 ID - Salanti2014 ER - TY - JOUR AU - Rubin, L. AU - Mendoza, J. AU - Hood, M. AU - McGoon, M. AU - Barst, R. AU - Williams, W. AU - Diehl, J. AU - Crow, J. AU - Long, W. PY - 1990 DA - 1990// TI - Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol) JO - Ann Intern Med VL - 112 ID - Rubin1990 ER - TY - JOUR AU - Barst, R. AU - Rubin, L. AU - Long, W. AU - McGoon, M. AU - Rich, S. AU - Badesch, D. AU - Groves, B. AU - Tapson, V. AU - Bourge, R. AU - Brundage, B. PY - 1996 DA - 1996// TI - A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension JO - N Engl J Med VL - 334 ID - Barst1996 ER - TY - JOUR AU - Anderson, R. J. AU - Malhotra, A. AU - Kim, N. H. PY - 2016 DA - 2016// TI - Pulmonary hypertension: evolution of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension JO - J Thorac Dis VL - 8 ID - Anderson2016 ER - TY - JOUR AU - Humbert, M. AU - Barst, R. AU - Robbins, I. AU - Channick, R. AU - Galie, N. AU - Boonstra, A. AU - Rubin, L. AU - Horn, E. AU - Manes, A. AU - Simonneau, G. PY - 2004 DA - 2004// TI - Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2 JO - Eur Respir J VL - 24 ID - Humbert2004 ER - TY - JOUR AU - Simonneau, G. AU - Rubin, L. AU - Galie, N. AU - Barst, R. AU - Fleming, T. AU - Frost, A. AU - Engel, P. AU - Kramer, M. AU - Burgess, G. AU - Collings, L. PY - 2008 DA - 2008// TI - Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension JO - Ann Intern Med VL - 149 ID - Simonneau2008 ER - TY - STD TI - McLaughlin V, Channick R, Ghofrani H, Lemarie J, Naeije R, Packer M, Souza R, Tapson V, Tolson J, Al Hiti H, et al. Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension. Eur Respir J. 2015; In Press. ID - ref82 ER - TY - JOUR AU - LeVarge, B. L. AU - Channick, R. N. PY - 2015 DA - 2015// TI - The changing paradigm in pulmonary hypertension trials: longer duration, new endpoints JO - Curr Opin Pulm Med VL - 21 ID - LeVarge2015 ER - TY - JOUR AU - McLaughlin, V. V. AU - Badesch, D. B. AU - Delcroix, M. AU - Fleming, T. R. AU - Gaine, S. P. AU - Galie, N. AU - Gibbs, J. S. AU - Kim, N. H. AU - Oudiz, R. J. AU - Peacock, A. PY - 2009 DA - 2009// TI - End points and clinical trial design in pulmonary arterial hypertension JO - J Am Coll Cardiol VL - 54 ID - McLaughlin2009 ER - TY - BOOK PY - 2009 DA - 2009// TI - Guideline on the clinical investigations of medicinal products for the treatment of pulmonary arterial hypertension ID - ref85 ER - TY - JOUR AU - Sitbon, O. AU - Gomberg-Maitland, M. AU - Granton, J. PY - 2019 DA - 2019// TI - Clinical trial design and new therapies for pulmonary arterial hypertension JO - Eur Respir J VL - 53 ID - Sitbon2019 ER - TY - JOUR AU - Fritz, J. S. AU - Blair, C. AU - Oudiz, R. J. AU - Dufton, C. AU - Olschewski, H. AU - Despain, D. AU - Gillies, H. AU - Kawut, S. M. PY - 2013 DA - 2013// TI - Baseline and follow-up 6-min walk distance and brain natriuretic peptide predict 2-year mortality in pulmonary arterial hypertension JO - Chest VL - 143 ID - Fritz2013 ER - TY - JOUR AU - Olschewski, H. AU - Simonneau, G. AU - Galie, N. AU - Higenbottam, T. AU - Naeije, R. AU - Rubin, L. AU - Nikkho, S. AU - Speich, R. AU - Hoeper, M. PY - 2002 DA - 2002// TI - Inhaled Iloprost for severe pulmonary hypertension JO - N Engl J Med VL - 347 ID - Olschewski2002 ER -