Table 2 A summary of previous reports of SR in lung cancer
Authors | Age | Gender | Staging | Histology | Degree of Remission | Follow-Up Duration | Relapse or Death | Potential Trigger Identified | Previous / Subsequent Treatment / Outcomes Details | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
Primary | Nodes | Metastases | |||||||||
Jeong et al. 2019 [24] | 64 | M | T1c NX MX | Squamous cell carcinoma | Complete | Not applicable | Not applicable | 16 | Local relapse | Biopsy | • Neoadjuvant chemo on relapse • Lobectomy (ypT0 N2) • Adjuvant chemo + RT • Unknown follow-up |
Matsui et al. 2018 [25] | 56 | F | T1a N2 M0 | Squamous cell carcinoma | Partial | None | Not applicable | 12 | No | Biopsy | • Lobectomy (ypT1a N2) • No adjuvant treatment • Disease-free at 1 year |
Ooi et al. 2018 [26] | 77 | M | T3 N1 M0 | Not otherwise specified | Partial | Complete | Not applicable | 24 | No | None | • Surveillance ongoing |
Ariza-Prota et al. 2018 [19] | 82 | M | T3 N3 M1c | Squamous cell carcinoma | Partial | Partial | Complete | 12 | No | Biopsy | • Palliative thoracic RT • Death 1 year later (MI) |
Esplin et al. 2018 [27] | 57 | M | T1b N0 M0 | Squamous cell carcinoma | Partial | Not applicable | Not applicable | Not reported | Not reported | Biopsy | Not reported |
Miyoshi et al. 2017 [28] | 80 | M | Not reported | Adenocarcinoma | Partial | Not applicable | Not applicable | 31 | No | Biopsy | • Surveillance ongoing |
Marques et al. 2017 [29] | 75 | M | T1b N0 M0 | Adenocarcinoma | Complete | Not applicable | Not applicable | 36 | No | Biopsy | • Surveillance ongoing |
Lopez-Pastorini et al. 2015 [30] | 76 | M | T3 N2 M0 | Large cell carcinoma | Partial | Partial | Not applicable | 84 | No | Biopsy | • Surveillance ongoing |
Choi et al. 2013 [31] | 71 | M | Not reported | Squamous cell carcinoma | Partial | Not applicable | Not applicable | Not reported | No | Tuberculosis | • Surveillance ongoing |
Kappauf et al. 1997 [32] | 61 | M | TX NX M1b | Adenocarcinoma | Not Applicable | Not applicable | Complete | 78 | No | Biopsy | • Lobectomy 7/12 earlier |
Park et al. 2016 [33] | 79 | M | TX NX M1a | Squamous cell carcinoma | Partial | Partial | Partial | 14 | No | Ginseng | Not reported |
Ogawa et al. 2015 [34] | 65 | M | TX NX M1c | Not otherwise specified | Partial | Partial | Partial | Not reported | Not reported | Biopsy | • Palliative RT given for MSCC after SR had began |
Kwint et al. 2015 [35] | 80 | M | T2a N3 M1b* | Not otherwise specified | Partial | Partial | Complete | 6 | No | None | Not reported |
Cafferata et al. 2004 [36] | 68 | M | T1c N0 M0 | Adenocarcinoma | Complete | Not applicable | Not applicable | 48 | No | None | Not reported |
Chung et al. 2015 [37] | 67 | M | T4 N0 M1b | Squamous cell carcinoma | Partial | Not applicable | Not reported | 13 | No | Herbal medicine | Not reported |
Menon et al. 2015 [38] | 44 | M | T1b N0 M1c | Not otherwise specified | Partial | Not applicable | Complete | 60 | No | HAART | • WBRT at diagnosis • HAART adherence increased |
Hwang et al. 2013 [39] | 62 | M | T2a N3 M0 | Not otherwise specified | Complete | Partial | Not applicable | 14 | No | None | • Declined all treatment |
Mizuno et al. 2011 [40] | 62 | M | T1b N0 M0 | Large cell carcinoma | Complete | Not applicable | Not applicable | 6 | Distant Relapse | Biopsy/Surgery | • Palliative chemo |
Nakamura et al. 2009 [41] | 71 | M | T4 N0 M0 | Adenocarcinoma | Disease Progression | Not applicable | Complete | 34 | No | Immunological | • Palliative RT to hilum |
Pujol et al. 2007 [42] | 75 | F | Localised but no staging | Squamous cell carcinoma | Complete | Not applicable | Not applicable | 18 | No | Anti-Hu paraneoplastic syndrome | • Plasmapheresis |
Miyazaki et al. 2007 [43] | 74 | M | TX N0 M1b | Adenocarcinoma | None | Not applicable | Complete | 35 | No | None | • Received radical RT to the primary eventually |
Furukawa et al. 2011 [44] | 56 | M | T1 N0 M0* | Squamous cell carcinoma | Partial | Not applicable | Not applicable | 2 | No | Bullous disease | • Resected after 2 months |
Gladwish et al. 2010 [45] | 84 | F | T3 N3 M0 | Squamous cell carcinoma | Partial | Partial | Not applicable | 12 | No | None | • No treatment accepted |
Yoon et al. 2019 [46] | 74 | F | T3 N1 M0 | Not otherwise specified | Partial | Partial | Not applicable | 9 | No | Herbal medicine | • Progressed through 6 lines of palliative chemo • SR noted one year following cessation of chemo |
Leo et al. 1999 [47] | 59 | M | T1c N1 M0 | Large cell carcinoma | Complete | Not applicable | Not applicable | 4 | No | Inadequate vasculature | • Appearance of LN during SR • Lobectomy, bronchial sleeve resection and LN sampling performed |
Tomizawa et al. 2014 [48] | 85 | F | T1c N0 M0 | Large cell carcinoma | Partial | Not applicable | Not applicable | 13 | Local relapse | Immunological | • SR ended on commencing glucocorticoids for inflammatory arthritis • Lobectomy on relapse |