Table 1 Study population and baseline characteristics
Characteristic | Surfactant n = 22 | Control n = 22 | P Value |
|---|---|---|---|
Age (months) | 5.5(±1.6) | 5.3(±1.8) | 0.698 |
Weight (kg) | 6.2(±1.2) | 6.3(±1.5) | 0.808 |
Sex (male/female) | 13/9 | 12/10 | 0.585 |
RACHS-1 II (%) | 7(31.8) | 7(31.8) | |
RACHS-1 III (%) | 8(36.3) | 8(36.3) | |
RACHS-1 IV (%) | 7(31.8) | 7(31.8) | |
Total on-pump time (min) | 146.8(±44.5) | 138.4(±35.8) | 0.382 |
Aortic clamping time (min) | 57.3(±18.1) | 52.3(±15.2) | 0.326 |
Time of inclusion (days after operation) | 3.0(±1.6) | 2.9(±1.4) | 0.826 |
OI | 13.9(±3.8) | 13.2(±3.2) | 0.512 |
VI | 42.4(±7.6) | 40.6(±8.4) | 0.460 |
PaO2/FiO2 | 88.5(±15.4) | 90.3(±17.5) | 0.719 |
PaCO2 | 43.0(±5.8) | 45.8(±7.5) | 0.173 |
SOFA score | 10.5(±2.9) | 11.2(±3.1) | 0.325 |
Use of neuromuscular blockers (%) | 12(54.5) | 14(63.6) | 0.106 |
Vasopressor use (%) | 22(100) | 22(100) | |
Body temperature (°C) | 36.5(±0.4) | 36.4(±0.5) | 0.468 |
Mean arterial pressure (mmHg) | 44.6(±18.4) | 47.2(±15.6) | 0.616 |
White cell count (109/L) | 13.4(±4.2) | 12.1(±3.8) | 0.288 |
CRP (mg/L) | 58.6(±20.7) | 49.2(±16.1) | 0.100 |
Latate (mmol/L) | 1.1(±0.4) | 0.8(±0.3) | 0.013 |
Creatinine (umol/L) | 64.8(±32.2) | 72.1(±20.5) | 0.375 |
Clinical pneumonia+ CPB injury (%) | 10(45.5) | 12(54.5) | 0.818 |
Proved pneumonia (%) | 7(31.8) | 9(40.9) | 0.358 |
Viral, non-RSV (%) | 2(9) | 3(13.6) | 0.000 |
RSV (%) | 1(4.5) | 2(9) | 0.000 |
Bacterial (%) | 3(13.6) | 4(18) | 0.003 |
CPB injury (%) | 12(54.5) | 10(45.5) | 0.818 |