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Table 2 Comparison of Clinical Features Between Convex Pattern and Non-convex Pattern of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

  Convex pattern (n = 93) Non-convex pattern (n = 37) p value
Age, years 72 (65–77) 69 (64–75) 0.183
Gender (male/female) 70 (75.3%)/23 (24.7%) 34 (91.9%)/3 (8.1) 0.033*
BMI, kg/m2 22.4 (20.2–24.7) 23.6 (22.9–28.8) < 0.001
Pack-years 26 (0–41) 39 (21–60) 0.007
FVC %pred., % 76.1 (62.6–89.2) 78.8 (65.7–89.4) 0.488
FEV1%pred., % 79.2 (68.3–92.8) 71.3 (64.5–84.3) 0.059
DLCO %pred., % 70.1 (50.2–87.6)** 68.4 (54.4–77.9) 0.552
CPI 31.8 (19.1–47.6)** 31.5 (17.6–43.5) 0.755
KL-6, U/ml 960 (603–1717)*** 953 (628–1458) 0.460
GAP stage 1 (1–2)** 1 (1–2) 0.377
  1. Data are presented as number or median (interquartile range)
  2. p values derived by Mann–Whitney U test. *p values derived by chi-square test
  3. **n = 87 and ***n = 92
  4. BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lungs for carbon monoxide, CPI composite physiologic index, KL-6 Krebs von den Lungen-6, GAPs gender, age, and physiology