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Table 2 Comparison of Clinical Features Between Convex Pattern and Non-convex Pattern of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

 

Convex pattern (n = 93)

Non-convex pattern (n = 37)

p value

Age, years

72 (65–77)

69 (64–75)

0.183

Gender (male/female)

70 (75.3%)/23 (24.7%)

34 (91.9%)/3 (8.1)

0.033*

BMI, kg/m2

22.4 (20.2–24.7)

23.6 (22.9–28.8)

< 0.001

Pack-years

26 (0–41)

39 (21–60)

0.007

FVC %pred., %

76.1 (62.6–89.2)

78.8 (65.7–89.4)

0.488

FEV1%pred., %

79.2 (68.3–92.8)

71.3 (64.5–84.3)

0.059

DLCO %pred., %

70.1 (50.2–87.6)**

68.4 (54.4–77.9)

0.552

CPI

31.8 (19.1–47.6)**

31.5 (17.6–43.5)

0.755

KL-6, U/ml

960 (603–1717)***

953 (628–1458)

0.460

GAP stage

1 (1–2)**

1 (1–2)

0.377

  1. Data are presented as number or median (interquartile range)
  2. p values derived by Mann–Whitney U test. *p values derived by chi-square test
  3. **n = 87 and ***n = 92
  4. BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lungs for carbon monoxide, CPI composite physiologic index, KL-6 Krebs von den Lungen-6, GAPs gender, age, and physiology