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Table 3 Comparison of Clinical Features Between Concave Pattern and Non-concave Pattern of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

 

Concave pattern (n = 72)

Non-concave pattern (n = 58)

p value

Age, years

69 (63–75)

73 (66–77)

0.034

Gender (male/female)

58 (80.6%)/14 (19.4%)

46 (79.3%)/12 (20.7%)

0.860*

BMI, kg/m2

23.9 (22.1–26.5)

21.1 (19.8–23.5)

< 0.001

Pack-years

30 (4–46)

25 (1–47)

0.558

FVC %pred., %

79.7 (68.4–92.9)

68.1 (59.1–86.2)

0.011

FEV1%pred., %

75.9 (66.2–89.2)

76.9 (64.1–92.8)

0.912

DLCO %pred., %

70.8 (53.8–84.0)**

67.7 (46.1–86.9)***

0.330

CPI

28.7 (18.7–40.9)**

35.8 (18.3–50.3)***

0.039

KL-6, U/ml

956 (648–1476)****

979 (565–1544)

0.919

GAP stage

1 (1–2)**

2 (1–2) ***

0.033

  1. Data are presented as number or median (interquartile range)
  2. p values derived by Mann–Whitney U test. *p values derived by chi-square test
  3. **n = 70, ***n = 54, and ****n = 71
  4. BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lungs for carbon monoxide, CPI composite physiologic index, KL-6 Krebs von den Lungen-6, GAP gender, age, and physiology
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BMC Pulmonary Medicine

ISSN: 1471-2466

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