A group (n = 47) | B group (n = 25) | C group (n = 46) | D group (n = 12) | p value | |
---|---|---|---|---|---|
Age, years | 68 (63–76) | 69 (64–75) | 73 (69–78) | 71 (63–75) | 0.104 |
Gender (male/female) | 35/12 | 23/2 | 35/11 | 11/1 | 0.203* |
BMI, kg/m2 | 23.6 (21.4–26.0) | 25.4 (23.1–29.3) | 20.8 (19.5–23.5) | 23.0 (20.7–25.3) | < 0.001 |
Pack-years | 27 (0–40) | 40 (22–56) | 19 (0–44) | 38 (8–70) | 0.064 |
FVC %pred., % | 81.4 (68.2–98.4) | 76.2 (67.1–86.7) | 67.0 (57.9–84.4) | 81.2 (65.1–98.8) | 0.018 |
FEV1%pred., % | 81.1 (69.9–93.8) | 68.2 (64.8–80.0) | 76.3 (65.2–91.4) | 78.2 (63.8–98.8) | 0.103 |
DLCO %pred., % | 73.8 (53.1–86.6) ** | 69.6 (55.1–82.4) | 68.8 (46.2–90.2)*** | 71.3 (43.2–77.7) | 0.812 |
CPI | 27.3 (19.7–40.7)** | 31.1 (14.6–41.3) | 35.8 (17.1–49.9)*** | 29.3 (21.7–49.8) | 0.226 |
KL-6, U/ml | 935 (686–1568) | 960 (467–1519) | 1070 (502–1776) | 918 (652–1088) | 0.883 |
GAP stage | 1 (1–2)** | 1 (1–2) | 2 (1–-2)*** | 2 (1–2) | 0.125 |