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Table 6 Comparison of Radiological Features Between Concave Pattern and Non-concave Pattern of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

  Concave pattern (n = 72) Non-concave pattern (n = 58) p value
Total lung area, L 3.60 (3.16–4.28) 3.47 (2.81–4.04) 0.161
HA, ml 83 (44–151) 118 (75–187) 0.017
%HA, % 2.4 (1.2–4.1) 3.5 (2.1–6.5) 0.009
sLAA, ml 205 (119–363) 220 (73–418) 0.881
%sLAA, % 5.9 (3.7–8.0) 6.0 (2.9–11.0) 0.815
Upper/peripheral %HA, % 1.2 (0.6–2.9) 2.4 (1.2–5.2) 0.001
Upper/central %HA, % 0.1 (0.0–0.3) 0.2 (0.0–0.7) 0.048
Lower/peripheral %HA, % 4.6 (2.8–7.6) 6.6 (4.2–10.2) 0.029
Lower/central %HA, % 0.7 (0.2–2.3) 1.7 (0.5–4.0) 0.022
Upper/peripheral %sLAA, % 6.8 (4.5–9.8) 6.5 (3.8–11.2) 0.538
Upper/central %sLAA, % 7.2 (4.7–11.2) 7.6 (3.6–12.7) 0.687
Lower/peripheral %sLAA, % 4.6 (2.9–7.1) 5.1 (2.5–8.7) 0.558
Lower/central %sLAA, % 4.9 (3.4–7.6) 6.0 (2.6–10.1) 0.579
  1. Data are presented as median (interquartile range)
  2. p values derived by Mann–Whitney U test
  3. %HA, computed-tomography-derived %honeycombing area; %sLAA, computed-tomography-derived %subtracted low attenuation area