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Table 7 Comparison of Radiological Features Among Four groups of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

 

A group

(n = 47)

B group

(n = 25)

C group

(n = 46)

D group

(n = 12)

p value

Total lung area, L

3.64 (3.19–4.40)

3.56 (2.98–3.96)

3.43 (2.72–3.99)

3.67 (3.21–4.86)

0.270

HA, ml

81 (44–157)

84 (43–141)

124 (75–193)

101 (72–130)

0.085

%HA, %

2.4 (1.2–4.0)

2.3 (1.2–4.5)

4.2 (2.1–6.8)

3.1 (2.2–4.1)

0.046

sLAA, ml

207 (110–375)

180 (135–337)

203 (69–372)

389 (115–553)

0.264

%sLAA, %

6.1 (3.4–8.0)

5.7 (4.3–8.0)

5.6 (2.7–9.4)

9.1 (3.5–15.7)

0.291

Upper/peripheral %HA, %

1.2 (0.6–2.9)

1.4 (0.5–2.7)

3.1 (1.3–5.5)

1.5 (1.1–2.5)

0.005

Upper/central %HA, %

0.1 (0.0–0.4)

0.1 (0.0–0.2)

0.2 (0.1–1.0)

0.1 (0.0–0.2)

0.069

Lower/peripheral %HA, %

4.7 (2.9–7.4)

4.5 (2.6–7.7)

7.1 (3.9–11.5)

5.8 (4.6–6.8)

0.131

Lower/central %HA, %

0.7 (0.2–2.1)

0.9 (0.2–2.6)

1.7 (0.6–4.1)

0.8 (0.3–3.3)

0.113

Upper/peripheral %sLAA, %

6.8 (4.2–9.7)

6.7 (5.9–10.9)

6.0 (3.7–6.0)

10.1 (4.0–14.1)

0.297

Upper/central %sLAA, %

7.1 (4.7–11.1)

7.7 (6.0–13.4)

6.5 (3.6–11.9)

10.2 (3.3–17.5)

0.529

Lower/peripheral %sLAA, %

4.9 (2.5–7.7)

4.4 (3.2–6.8)

4.6 (2.3–7.6)

7.7 (4.2–12.8)

0.151

Lower/central %sLAA, %

5.0 (3.0–7.6)

4.7 (3.7–7.9)

5.8 (2.5–8.8)

8.5 (3.4–16.6)

0.304

  1. Data are presented as number or median (interquartile range)
  2. p values derived by Kruskal-Wallis test
  3. A group, the patients with the convex/concave pattern of flow volume curve; B group, the non-convex/concave pattern; C group, the convex/non-concave pattern; D group, the non-convex/non-concave pattern
  4. %HA, computed-tomography-derived %honeycombing area; %sLAA, computed-tomography-derived %subtracted low attenuation area