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Table 7 Comparison of Radiological Features Among Four groups of Flow-volume Curve

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

  A group
(n = 47)
B group
(n = 25)
C group
(n = 46)
D group
(n = 12)
p value
Total lung area, L 3.64 (3.19–4.40) 3.56 (2.98–3.96) 3.43 (2.72–3.99) 3.67 (3.21–4.86) 0.270
HA, ml 81 (44–157) 84 (43–141) 124 (75–193) 101 (72–130) 0.085
%HA, % 2.4 (1.2–4.0) 2.3 (1.2–4.5) 4.2 (2.1–6.8) 3.1 (2.2–4.1) 0.046
sLAA, ml 207 (110–375) 180 (135–337) 203 (69–372) 389 (115–553) 0.264
%sLAA, % 6.1 (3.4–8.0) 5.7 (4.3–8.0) 5.6 (2.7–9.4) 9.1 (3.5–15.7) 0.291
Upper/peripheral %HA, % 1.2 (0.6–2.9) 1.4 (0.5–2.7) 3.1 (1.3–5.5) 1.5 (1.1–2.5) 0.005
Upper/central %HA, % 0.1 (0.0–0.4) 0.1 (0.0–0.2) 0.2 (0.1–1.0) 0.1 (0.0–0.2) 0.069
Lower/peripheral %HA, % 4.7 (2.9–7.4) 4.5 (2.6–7.7) 7.1 (3.9–11.5) 5.8 (4.6–6.8) 0.131
Lower/central %HA, % 0.7 (0.2–2.1) 0.9 (0.2–2.6) 1.7 (0.6–4.1) 0.8 (0.3–3.3) 0.113
Upper/peripheral %sLAA, % 6.8 (4.2–9.7) 6.7 (5.9–10.9) 6.0 (3.7–6.0) 10.1 (4.0–14.1) 0.297
Upper/central %sLAA, % 7.1 (4.7–11.1) 7.7 (6.0–13.4) 6.5 (3.6–11.9) 10.2 (3.3–17.5) 0.529
Lower/peripheral %sLAA, % 4.9 (2.5–7.7) 4.4 (3.2–6.8) 4.6 (2.3–7.6) 7.7 (4.2–12.8) 0.151
Lower/central %sLAA, % 5.0 (3.0–7.6) 4.7 (3.7–7.9) 5.8 (2.5–8.8) 8.5 (3.4–16.6) 0.304
  1. Data are presented as number or median (interquartile range)
  2. p values derived by Kruskal-Wallis test
  3. A group, the patients with the convex/concave pattern of flow volume curve; B group, the non-convex/concave pattern; C group, the convex/non-concave pattern; D group, the non-convex/non-concave pattern
  4. %HA, computed-tomography-derived %honeycombing area; %sLAA, computed-tomography-derived %subtracted low attenuation area