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Table 8 Results of Cox’s Hazard Regression Analysis for Predictors of Mortality Adjusted by Age, Gender, BMI, and Pack-year

From: Relationship of flow-volume curve pattern on pulmonary function test with clinical and radiological features in idiopathic pulmonary fibrosis

  HR 95% CI p value
C group (vs non-C group) 2.19 1.07–4.49 0.032
FVC %pred., % 0.97 0.94–0.99 0.002
FEV1%pred., % 0.99 0.97–1.01 0.289
DLCO %pred., % 0.97 0.95–0.99 0.002
CPI 1.05 1.02–1.08 < 0.001
GAP stage 1.93 0.98–3.74 0.057
KL-6, U/ml 1.00 1.00–1.00 0.360
%HA, % 1.26 1.13–1.40 < 0.001
%sLAA, % 0.98 0.90–1.06 0.665
Convex pattern
(vs Non-convex pattern)
1.67 0.84–3.50 0.143
Concave pattern
(vs Non-concave pattern)
0.56 0.29–1.10 0.091
  1. HR hazard ratio, CI confidence interval, %HA computed-tomography-derived %honeycombing area, %sLAA computed-tomography-derived %subtracted low attenuation area, BMI body mass index, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, DLCO diffusing capacity of the lungs for carbon monoxide, CPI composite physiologic index, KL-6 Krebs von den Lungen-6, GAP gender, age, and physiology