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Table 1 Laboratory test

From: Double anti-PL-7 and anti-MDA-5 positive Amyopathic Dermatomyositis with rapidly progressive interstitial lung disease in a Hispanic patient

Test name Value (reference range)
Hematology
 White blood count 9.1 103/uL at Day 1 of admission
Range from 5.3–9.7 103/uL during hospital stay (4.0–11.0 103/uL)
 Hemoglobin 12.8 g/dL at Day 1 of admission
Range from 6.1–12.8 g/dL during hospital stay (12-16 g/dL)
 Platelet count 260 103/uL at Day 1 of admission
Range from 68.0–260 103/uL during stay (140–440 103/uL)
Chemistry
Aldolase 12.4 (< 8.2 U/L)
Creatine kinase 17 to 26 U/L during admission (25–140 U/L)
Alanine aminotransferase (ALT) 15 to 227 U/L during admission (7-35 U/L)
  Lactic Acid 2.1 mmol/L at day 1 of admission
Range from 0.9–4.1 mmol/L during admission stay
Infectious
 Culture, Blood No growth
 Culture, Respiratory aspiration No growth
 Culture, Fungal in respiratory aspiration No growth
 Culture, Urine No growth
 Cocci-Direct PCR Negative
 Legionella Urine antigen Negative
 Mycoplasma Pnuemoniae Negative
 Strep Pneumoniae Urine antigen Positive
 Upper respiratory viral panels Negative
 Influenza A/B PCR Negative
 HIV AB AG screen Negative
Autoimmune
 Anti-neutrophil cytoplasmic antibody (ANCA) Negative
 Antinuclear antibody reflex (ANA) Positive, titer 1:160
 SS-A/Ro IgG antibody 1.2 positive (< 1.0 Negative)
 SS-B/La IgG antibody < 1.0Negative (< 1.0 Negative)
 Anti-topoisomerase (SCL-70) IgG antibody < 1.0 Negative (< 1.0 Negative)
 Centromere auto antibody < 1.0 Negative (< 1.0 Negative)
 Double strand DNA (dsDNA) 1 IU/mL (< 5 IU/mL)
 Smith IgG < 1.0 negative (< 1.0 Negative)
 Ribonucleic protein (U1 RNP/snRNP) IgG < 1.0 negative (< 1.0 Negative)
 Myositis panel (collection date: Hospital Day 8) Jo-1 Ab < 11 (< 11 SI)
PL-7 Ab 60 (< 11 SI)
PL-12 Ab < 11 (< 11 SI)
EJ Ab < 11 (< 11 SI)
OJ Ab < 11 (< 11 SI)
SRP Ab < 11 (< 11 SI
Mi-2 Alpha Ab < 11(< 11 SI)
Mi-2 Beta Ab < 11 (< 11 SI)
MDA-5 Ab 89 (< 11 SI)
TIF-1y Ab < 11 (< 11 SI)
NXP-2 Ab < 11 (< 11 SI)
 Myositis panel (collection date: Hospital Day 16) Jo-1 Ab < 11 (< 11 SI)
PL-7 Ab61 (< 11 SI)
PL-12 Ab < 11 (< 11 SI)
EJ Ab < 11 (< 11 SI)
OJ Ab < 11 (< 11 SI)
SRP Ab < 11 (< 11 SI
Mi-2 Alpha Ab < 11(< 11 SI)
Mi-2 Beta Ab < 11 (< 11 SI)
MDA-5 Ab 78 (< 11 SI)
TIF-1y Ab < 11 (< 11 SI)
NXP-2 Ab < 11 (< 11 SI)
  1. Jo-1 (antihistidyl-tRNA synthetase), PL-7 (threonyl), PL-12 (alanyl), EJ (glycyl), OJ (isoleucyl), Mi-2 (Mi-2/nucleosome remodelling and deacetylase (NuRD), SRP (signal recognition particle), MDA5 (melanoma-differentiation associated gene 5), TIF-1 y (intermediary factor 1-gamma), NXP-2(nuclear matrix protein),