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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: miRNA-425-5p enhances lung cancer growth via the PTEN/PI3K/AKT signaling axis

Fig. 5

Effects of miR-425-5p on PTEN/PI3K/AKT. a. WB analysis of PTEN, PI3K, p-AKT, and AKT in LCa cells. Full-length blots/gels are presented in Supplementary Figure 3. b The PI3K kinase activity was determined in NSCLC cells transfected with LY294002 was significantly lower than that transfected with mimic control, and the PI3K kinase activity in NSCLC transfected with both LY294002 and miR-425-5p mimic was significantly higher than that transfected with LY294002. Data: mean ± SD. * P < 0.05; ** P < 0.01; *** P < 0.001

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