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Table 1 Demographic data, latent tuberculosis screening results and medication of patients with rheumatic diseases

From: Chest roentgenography is complementary to interferon-gamma release assay in latent tuberculosis infection screening of rheumatic patients

 

Total

N = 238

RA

N = 183

AS

N = 34

PsA

N = 21

Age (mean ± SD)

55.4 ± 14.8

56.9 ± 13.2a

41.8 ± 14.7

41.5 ± 13.0

Sex (M/F)

73/165

34/149 b

27/7

12/9

Medication n (%)

 MTX

104 (43.7)

102 (55.7)

1 (2.9)

1 (4.8)

 LEF

78 (33.8)

62 (33.9)

1 (2.9)

15 (71.4)

 SSZ

128 (53.8)

92 (50.3)

26 (76.5)

10 (47.6)

 HCQ

61 (25.6)

59 (32.2)

1 (2.9)

1 (4.8)

 Glucocorticoid

127 (53.4)

114 (62.3)

4 (11.8)

9 (42.9)

 Pred. dose (mg)

3.6

4.2

0.7

3.0

 NSAIDs

194 (81.5)

150 (82.0)

30 (88.2)

14 (66.7)

 Biologics

207 (87.0)

155 (84.7)

32 (94.1)

20 (95.2)

 TNFi

179 (75.2)

131 (71.6)

32 (94.1)

16 (76.2)

 non-TNFi

28 (11.8)

24 (13.1)

0 (0)

4 (19.0)

Screening results

IGRA P/N/IND n

(%)

46/178/14

(19.3/74.8/5.9)

37/132/14

(20.2/72.1/7.7)

8/26/0

(23.5/76.5/0)

1/20/0

(4.8/95.2/0)

 CXR-old-TB n (%)

43 (18.1)

34 (18.6)

6 (17.6)

3 (14.3)

  1. a RA vs. AS or PsA (p < 0.001 by ANOVA). b RA vs AS or PsA (p < 0.001by Chi-square test)
  2. RA rheumatoid arthritis, AS ankylosing spondylosis, PsA psoriatic arthritis, MTX methotrexate, LEF leflunomide, Pre. dose glucocorticoid equivalent dose in prednisolone, SSZ sulfasalazine, HCQ hydroxychloroquine, NSAID non-steroidal anti-inflammatory drug, TNFi TNF- inhibitor, IGRA interferon-gamma release assay, IND indeterminate, N negative, P positive, CXR-old-TB radiological evidence of previous tuberculosis infection