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Table 1 Demographic data, latent tuberculosis screening results and medication of patients with rheumatic diseases

From: Chest roentgenography is complementary to interferon-gamma release assay in latent tuberculosis infection screening of rheumatic patients

  Total
N = 238
RA
N = 183
AS
N = 34
PsA
N = 21
Age (mean ± SD) 55.4 ± 14.8 56.9 ± 13.2a 41.8 ± 14.7 41.5 ± 13.0
Sex (M/F) 73/165 34/149 b 27/7 12/9
Medication n (%)
 MTX 104 (43.7) 102 (55.7) 1 (2.9) 1 (4.8)
 LEF 78 (33.8) 62 (33.9) 1 (2.9) 15 (71.4)
 SSZ 128 (53.8) 92 (50.3) 26 (76.5) 10 (47.6)
 HCQ 61 (25.6) 59 (32.2) 1 (2.9) 1 (4.8)
 Glucocorticoid 127 (53.4) 114 (62.3) 4 (11.8) 9 (42.9)
 Pred. dose (mg) 3.6 4.2 0.7 3.0
 NSAIDs 194 (81.5) 150 (82.0) 30 (88.2) 14 (66.7)
 Biologics 207 (87.0) 155 (84.7) 32 (94.1) 20 (95.2)
 TNFi 179 (75.2) 131 (71.6) 32 (94.1) 16 (76.2)
 non-TNFi 28 (11.8) 24 (13.1) 0 (0) 4 (19.0)
Screening results
IGRA P/N/IND n
(%)
46/178/14
(19.3/74.8/5.9)
37/132/14
(20.2/72.1/7.7)
8/26/0
(23.5/76.5/0)
1/20/0
(4.8/95.2/0)
 CXR-old-TB n (%) 43 (18.1) 34 (18.6) 6 (17.6) 3 (14.3)
  1. a RA vs. AS or PsA (p < 0.001 by ANOVA). b RA vs AS or PsA (p < 0.001by Chi-square test)
  2. RA rheumatoid arthritis, AS ankylosing spondylosis, PsA psoriatic arthritis, MTX methotrexate, LEF leflunomide, Pre. dose glucocorticoid equivalent dose in prednisolone, SSZ sulfasalazine, HCQ hydroxychloroquine, NSAID non-steroidal anti-inflammatory drug, TNFi TNF- inhibitor, IGRA interferon-gamma release assay, IND indeterminate, N negative, P positive, CXR-old-TB radiological evidence of previous tuberculosis infection