Table 1 Sensitivity rate of Pseudomonas aeruginosa isolated from sputum and BALF to commonly used antibiotics
Antibiotics | 2013–2015 | 2016–2018 | ||||
|---|---|---|---|---|---|---|
BALF | Sputum | P | BALF | sputum | P | |
Piperacillin | 75 | 57.3 | < 0.01 | 68.2 | 55.8 | P < 0.01 |
Cefoperazone/sulbactam | 72.7 | 58.1 | < 0.01 | 71.8 | 54.6 | P < 0.01 |
Ticarcillin/clavulanic acid | 40.3 | 12.4 | < 0.01 | 40.3 | 10.8 | P < 0.01 |
Piperacillin/tazobactam | 79.3 | 62.8 | < 0.01 | 74.6 | 61.7 | P < 0.01 |
Cefoperazone | 64.2 | 49.6 | < 0.01 | 65.1 | 48.2 | P < 0.01 |
Ceftazidime | 80.5 | 64.5 | < 0.01 | 73.4 | 62.3 | P < 0.01 |
Cefepime | 81.1 | 64.5 | < 0.01 | 78.1 | 68.5 | P < 0.01 |
Aztreonam | 71.3 | 53.8 | < 0.01 | 63.5 | 46.8 | P < 0.01 |
Imipenem | 72 | 63.2 | 0.01 < P < 0.05 | 68.6 | 57.4 | P < 0.01 |
Meropenem | 81 | 64.1 | < 0.01 | 74.4 | 61.7 | P < 0.01 |
Amikacin | 88.4 | 72.7 | < 0.01 | 87.6 | 86.4 | P > 0.05 |
Gentamicin | 82.1 | 61.8 | < 0.01 | 80.5 | 79.4 | P > 0.05 |
Tobramycin | 88.4 | 70.4 | < 0.01 | 87.8 | 84 | P > 0.05 |
Ciprofloxacin | 71.3 | 65 | P > 0.05 | 75.6 | 67.1 | P < 0.01 |
Levofloxacin | 64.2 | 58.1 | P > 0.05 | 68.9 | 61.2 | P < 0.01 |
Trimethoprim sulfamethoxazole | 21.6 | 7.8 | < 0.01 | 14.3 | 5.5 | P < 0.01 |
Minocycline | 35 | 13.2 | < 0.01 | 31.6 | 14 | P < 0.01 |