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Table 3 Sensitivity rate of Klebsiella pneumoniae isolated from sputum and BALF to commonly used antibiotics

From: Pathogenic characteristics of sputum and bronchoalveolar lavage fluid samples from patients with lower respiratory tract infection in a large teaching hospital in China: a retrospective study

Antibiotics

2013–2015

2016–2018

BALF

Sputum

P

BALF

Sputum

P

Piperacillin

31

23.7

P > 0.05

22.6

7

P < 0.01

Amoxicillin/clavulanic acid

59.6

43

P < 0.01

53.8

21.3

P < 0.01

Cefoperazone/sulbactam

70.4

53.9

P < 0.01

56.1

24.1

P < 0.01

Ampicillin/sulbactam

53.4

33.8

P < 0.01

49.7

15.7

P < 0.01

Piperacillin/tazobactam

75

61.1

P < 0.01

58.5

28.6

P < 0.01

Cefazolin

36.2

25.1

P < 0.01

42

12.8

P < 0.01

Cefuroxime

56

34

P < 0.01

49.9

16.6

P < 0.01

Ceftazidime

69.8

50.4

P < 0.01

54.8

23.8

P < 0.01

Cefotaxime

57.4

36.2

P < 0.01

51.9

17.9

P < 0.01

Cefepime

61.4

38.2

P < 0.01

53.8

19.2

P < 0.01

Cefoxitin

77.6

65.6

P < 0.01

59.2

32.6

P < 0.01

Aztreonam

69

48.9

P < 0.01

54.8

21.4

P < 0.01

Imipenem

90.5

81.3

0.01 < P < 0.05

67.3

40.3

P < 0.01

Meropenem

90.5

81

0.01 < P < 0.05

67.7

40.6

P < 0.01

Amikacin

87.8

83.3

P > 0.05

70.6

52.2

P < 0.01

Gentamicin

66.4

58.4

P > 0.05

61.4

38.5

P < 0.01

Tobramycin

61.2

55.5

P > 0.05

57.8

36.6

P < 0.01

Ciprofloxacin

69.6

60.4

P = 0.05

55.3

22.6

P < 0.01

Levofloxacin

75.9

71.2

P > 0.05

59.9

28.3

P < 0.01

Trimethoprim sulfamethoxazole

67.2

56.9

0.01 < P < 0.05

64.5

55.7

P < 0.01

Tegacycline

87.2

87.1

P > 0.05

92.3

89.2

P > 0.05