Table 2 Pooled means of sensitivity and specificity, diagnostic odds ratio (DOR), area under the curve (AUC) for each cytokine
From: The meta-analysis for ideal cytokines to distinguish the latent and active TB infection
Cytokine | Sensitivity (95% CI) | Specificity (95% CI) | DOR (95% CI) | AUC |
|---|---|---|---|---|
IL-2 | 0.87 (0.83–0.90) | 0.61 (0.57–0.66) | 13.62 (5.34–34.73) | 0.9093 |
IP-10 | 0.77 (0.72–0.81) | 0.73 (0.68–0.78) | 12.07 (4.453–32.73) | 0.8609 |
IL-5 | 0.64 (0.53–0.74) | 0.75 (0.62–0.85) | 11.93 (4.22–33.72) | 0.8533 |
IL-13 | 0.75 (0.66–0.83) | 0.71 (0.60–0.80) | 12.56 (1.82–86.82) | 0.8491 |
IFN-γ | 0.67 (0.61–0.73) | 0.75 (0.68–0.80) | 7.44 (3.57–15.51) | 0.8031 |
IL-10 | 0.68 (0.58–0.78) | 0.74 (0.63–0.83) | 8.20 (3.75–17.94) | 0.7957 |
TNF-α | 0.67 (0.56–0.77) | 0.64 (0.53–0.74) | 6.18 (2.58–14.81) | 0.7783 |