Safety of bronchoscopy in patients with malignant hematologic disorders

BMC Pulmonary Medicine

Table 1 Summary of 12 patients with prolonged oxygen desaturation (> 48 h) after bronchoscopy

Case	Underlying disease	Sedation	Platelet (× 103/μl)	Oxygen before bronchoscopy	Oxygen after bronchoscopy	Method	Clinical diagnosis	Hemoptysis	Outcome
1	ALL	Fentanyl 3 mg/hour	37	RA	1 L/min	Bronchial wash	Aspergillosis	–	Died after 2 months
2	AML	Peth 27.2 mg	20	RA	1 L/min	Bronchial wash	Unknown	–	Died after 3 weeks
3	AML	Peth 20.9 mg	9	RA	4 L/min	Bronchial wash	CMV pneumonia	+	Died after 9 days
4	ALL	Peth 18.5 mg	110	6 L/min	12 L/min	Bronchial wash	CMV pneumonia	–	Intubated, died after 1 month
5	AML/MDS	HH 25 mg	48	1 L/min	1 L/min	Bronchial wash	Aspergillosis	+	Died after 13 days
6	AML	Peth 25 mg	161	2 L/min	8 L/min	Bronchial wash	OP	–	Recovered
7	AML/MDS	Mid 1.5 mg, Peth 28 mg	38	RA	2 L/min	Bronchial wash	Underlying disease	–	Recovered
8	AML	Peth 27.3 mg	25	RA	RA	Bronchial wash	OP	–	Recovered
9	ALL	Peth 21 mg	384	RA	10 L/min	BAL, TBLB	Pneumocystis pneumonia	+	Intubated, recovered
10	AML	Mid 1.2 mg, Peth 27.0 mg	14	1 L/min	3 L/min	Bronchial wash	Unknown	–	Recovered
11	AML	Mid 1.5 mg, Peth 26.3 mg	98	RA	3 L/min	Bronchial wash	Underlying disease	–	Recovered
12	AML	Mid 2 mg, Peth 31.5 mg	171	RA	5 L/min	Bronchial wash	Aspergillosis	–	Recovered

ALL Acute lymphocytic leukemia, AML Acute myeloid leukemia, BAL Bronchoalveolar lavage, CBT Cord blood transplantation, CMV Cytomegalovirus, HH Hydroxyzine hydrochloride, MDS Myelodysplastic syndromes, Mid Midazolam, OP Organizing pneumonia, Peth Pethidine, RA Room air, rBMT Related BMT, rPBST Related peripheral blood stem cell transplantation, TBLB Transbronchial lung biopsy, uBMT Unrelated bone marrow transplantation

ISSN: 1471-2466