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Table 2 Risk factors for prolonged oxygen desaturation

From: Safety of bronchoscopy in patients with malignant hematologic disorders

Characteristic

Prolonged oxygen desaturation group (n = 12)

Improvement group (n = 304)

p value of univariate analysis

p value in multivariate analysis

Hazard ratio (95% CI)

Age ≤ 70 years

0

39

0.37

  

Sex (male/female)

10/2

225/79

0.74

  

AML and MPAL

9

153

0.09

0.19

 

Platelet count (≤20 × 103/μl)

3

26

0.05

0.12

 

Platelet transfusion

7

127

0.26

  

Neutrophil count (≤500)

2

61

1.00

  

Within 180 days from BMT except PBSCT

3

58

0.71

  

Inhalation of oxygen (≥5 L/min)

1

5

0.10

0.31

 

Bronchial wash

9

192

0.55

  

BAL

3

101

0.76

  

TBLB

2

119

0.14

0.15

 

Use of midazolam

5

230

0.01

0.03

0.28 (0.09–0.85)

Use of pethidine

10

251

1.00

  

Use of atropine sulfate

10

281

0.24

  
  1. Bold indicates statistical significance
  2. AML Acute myeloid leukemia, BAL Bronchoalveolar lavage, BMT Bone marrow transplantation;
  3. MPAL Mixed phonotype acute leukemia, PBST Peripheral blood stem cell transplantation, TBLB Transbronchial lung biopsy