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Table 1 Population characteristics and health status of 257 COPD patients of rural/semi-urban areas of Greece

From: Adherence to inhalers and comorbidities in COPD patients. A cross-sectional primary care study from Greece

Characteristics and health status

Total Group

N = 257

Good-Intermediate adherence

N = 59

(25.9%)

Poor adherence

N = 169 (74.1%)

P-value*

Age; mean (SD)

65 (12.3)

69.3 (13.4)

64.7 (12.0)

0.004

BMI; mean (SD)

29 (5.3)

29.7 (6.1)

29.3 (5.0)

0.603

Males; n (%)

204 (79.4)

45 (76.3)

133 (78.7)

0.837

Occupational status; n (%)

 Employed

74 (33.3)

10 (20.8)

52 (33.5)

0.038

 Unemployed/housewife

25 (11.3)

3 (6.3)

22 (14.2)

 Retired

123 (55.4)

35 (72.9)

81 (52.3)

Smoking status; n (%)

 Current

143 (55.6)

25 (42.4)

98 (58)

0.120

 Ex

83 (32.3)

25 (42.4)

50 (29.6)

 Never

31 (12.1)

9 (15.3)

21 (12.4)

Pack-years; median (IQR)

40 (10)

40 (60)

40 (10)

0.003

CAT score; mean (SD)

17.2 (6.7)

17.5 (7.3)

17.2 (5.7)

0.170

CAT score ≥ 10; n (%)

224 (91.1)

45 (83.3)

155 (95.1)

0.015

mMRC score; mean (SD)

1.9 (1.2)

1.7 (1.4)

2 (1.06)

0.759

mMRC score ≥ 2; n (%)

154 (60.6)

28 (47.1)

111 (66.5)

0.013

Number of exacerbations in the last 12 monthsa; median (IQR)

1 (1)

1 (1)

1 (1)

0.001

Exacerbations in the last 12 months; n (%)

0

55 (16.2)

16 (43.2)

37 (13.2)

 

1

167 (49.3)

16 (43.2)

136 (48.6)

< 0.001

≥ 2

117 (34.5)

5 (13.5)

107 (38.2)

 

Number of hospitalisations in the last 12 months; median (IQR)

0 (0)

0 (0)

0 (0)

0.913

Hospitalised in the last 12 months; n (%)

12 (5.2)

7 (15.2)

4 (2.1)

0.003

GOLD 2019 – CAT; n (%)

A

11 (5.4)

4 (13.8)

6 (3.8)

 

B

115 (56.4)

18 (62.1)

86 (54.4)

0.082

C

3 (1.5)

0 (0)

2 (1.3)

D

75 (36.8)

7 (24.1)

64 (40.5)

GOLD 2019 – mMRC; n (%)

A

57 (27.5)

14 (46.7)

38 (23.6)

 

B

71 (34.3)

9 (30.0)

56 (34.8)

0.055

C

20 (9.7)

1 (3.3)

16 (9.9)

D

59 (28.5)

6 (20.0)

51 (31.7)

  1. BMI Body mass index, IQR Interquartile range, GOLD 2019 Global Initiative for Obstructive Lung Disease 2019 Guidelines, CAT Chronic Obstructive Pulmonary Disease Assessment Test, mMRC Modified Medical Research Council Dyspnoea Scale
  2. *Chi-square or Fisher’s exact test for categorical variables, Student’s T-test for continuous variables with normal distribution and Mann-Whitney U test for not normally distributed variables
  3. aAn exacerbation was defined based on GOLD as “an event in the natural course of the disease characterized by a change in the patient’s baseline dyspnea, cough, and/or sputum that is beyond normal day-to-day variations, is acute in onset, and may warrant a change in regular medication to a patient with underlying COPD”, and patients were specifically asked whether they underwent such a change in the past 12 months