Fig. 5

ATR suppressed the inflammatory mediators and adhesion molecules in BALF. The inflammatory mediators (IL-6 and TNF-α) and adhesion molecules (ICAM-1 and P-selectin) were assessed with ELISA kits. Levels of (a) IL-6, (b) TNF-α, (c) P-selectin, and (d) ICAM-1 in BALF. Results were presented as mean ± SEM (n = 8 in each group). ^##P < 0.01 vs. the control group; ^*P < 0.05 vs. the CVF group; ^**P < 0.01 vs. the CVF group. ATR, atorvastatin; BALF, bronchoalveolar lavage fluid; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; ICAM-1, intercellular cell adhesion molecule-1; ELISA, enzyme-linked immunosorbent assay; CVF, cobra venom factor; SEM, standard error of the mean