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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis

Fig. 2

Correlation between the clinico-pathological features and MMP2 expression in lung cancer tissues. a MMP2 was highly expressed in lung cancer tissues, whereas it was lowly expressed in matched adjacent non-malignant tissues (p < 0.05). b Expression of MMP2 did not relate to the histological type of lung cancer patients (p > 0.05). c Upregulation of MMP2 was observed in poorly differentiated lung cancer tissues compared with well-differentiated tissues (p < 0.05). d Expression of MMP2 in lung cancer tissues at T3–4 stage was significantly higher than that in T1–2 stage (p < 0.05). e MMP2 expression in lung cancer tissues with N0-N1 of lymphnode metastasis was lower than that in those with N2-N3 of lymph node metastasis (p < 0.05). f Increase of MMP2 was displayed in tissues with lung cancer at stages III-IV compared with those at stages I-II (p < 0.05). MMP2, matrix metalloproteinase 2; SCLC, small cell lung cancer. LAC, lung adenocarcinoma. LSCC, lung squamous cell carcinoma. N, node stage (TNM classification)

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