Skip to main content

Table 2 Expression of MMP2 in lung cancer tissues (N = 65)

From: Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis

Parameter Group N Expression of MMP2
Low (%) Moderate (%) High (%) χ2 value P value
Category Normal 65 33 (50.8) 19 (29.2) 13 (20) 12.342 0.002
Cancerous 65 14 (21.5) 27 (41.5) 24 (37)
Gender Male 51 13 (25.5) 20 (39.2) 18 (35.3) 2.195 0.334
Female 14 1 (7.1) 7 (50) 6 (42.9)
Ages < 60 33 7 (21.2) 15 (45.5) 11 (33.3) 0.482 0.785
≥60 32 7 (21.9) 12 (37.5) 13 (40.6)
Smoking Yes 34 9 (26.5) 13 (38.2) 12 (35.3) 1.044 0.593
No 31 5 (16.1) 14 (45.2) 12 (38.7)
Histology LAC 25 5 (20) 13 (52) 7 (28) 2.011 0.734
LSCC 31 7 (22.6) 11 (35.5) 13 (41.9)
SCLC 9 2 (22.2) 3 (33.3) 4 (44.4)
Pathological grade Poorly 19 1 (5.3) 8 (42.1) 10 (52.6) 11.46 0.022
Moderately 23 4 (17.4) 11 (47.8) 8 (34.8)
Well 14 7 (50) 5 (35.7) 2 (14.3)
Unavailable 9 2 (22.2) 3 (33.3) 4 (44.4)
T staging T1-T2 37 11 (29.7) 18 (48.6) 8 (21.6) 10.567 0.032
T3-T4 19 1 (5.3) 6 (31.6) 12 (63.2)
Unavailable 9 2 (22.2) 3 (33.3) 4 (44.4)
Lymph node metastasis N0 - N1 23 10 (43.5) 11 (47.8) 2 (8.7) 17.06 < 0.001
N2 - N3 33 2 (6.1) 13 (39.4) 18 (54.5)
Unavailable 9 2 (22.2) 3 (33.3) 4 (44.4)
pTNM IA-IIB 36 11 (30.6) 18 (50) 7 (19.4) 12.59 0.002
IIIA-IV 20 1 (5) 6 (30) 13 (65)
Unavailable 9 2 (22.2) 3 (33.3) 4 (44.4)
  1. N, numbers of patients; p < 0.05, cancerous tissues compared with normal tissues; p < 0.05, Poorly differentiated tissues compared with well differentiated tissues; p < 0.05, T3–4 compared with T1–2; p < 0.05, N2-N3 of lymph node metastasis compared with N0-N1; p < 0.05, IIIA-IV compared with IA-IIB; LAC, lung adenocarcinoma; LSCC, lung squamous cell carcinoma; SCLC, small cell lung cancer