Table 2 Expression of MMP2 in lung cancer tissues (N = 65)
Parameter | Group | N | Expression of MMP2 | ||||
|---|---|---|---|---|---|---|---|
Low (%) | Moderate (%) | High (%) | χ2 value | P value | |||
Category | Normal | 65 | 33 (50.8) | 19 (29.2) | 13 (20) | 12.342 | 0.002 |
Cancerous | 65 | 14 (21.5) | 27 (41.5) | 24 (37)● | |||
Gender | Male | 51 | 13 (25.5) | 20 (39.2) | 18 (35.3) | 2.195 | 0.334 |
Female | 14 | 1 (7.1) | 7 (50) | 6 (42.9) | |||
Ages | < 60 | 33 | 7 (21.2) | 15 (45.5) | 11 (33.3) | 0.482 | 0.785 |
≥60 | 32 | 7 (21.9) | 12 (37.5) | 13 (40.6) | |||
Smoking | Yes | 34 | 9 (26.5) | 13 (38.2) | 12 (35.3) | 1.044 | 0.593 |
No | 31 | 5 (16.1) | 14 (45.2) | 12 (38.7) | |||
Histology | LAC | 25 | 5 (20) | 13 (52) | 7 (28) | 2.011 | 0.734 |
LSCC | 31 | 7 (22.6) | 11 (35.5) | 13 (41.9) | |||
SCLC | 9 | 2 (22.2) | 3 (33.3) | 4 (44.4) | |||
Pathological grade | Poorly | 19 | 1 (5.3) | 8 (42.1) | 10 (52.6)★ | 11.46 | 0.022 |
Moderately | 23 | 4 (17.4) | 11 (47.8) | 8 (34.8) | |||
Well | 14 | 7 (50) | 5 (35.7) | 2 (14.3) | |||
Unavailable | 9 | 2 (22.2) | 3 (33.3) | 4 (44.4) | |||
T staging | T1-T2 | 37 | 11 (29.7) | 18 (48.6) | 8 (21.6) | 10.567 | 0.032 |
T3-T4 | 19 | 1 (5.3) | 6 (31.6) | 12 (63.2)▲ | |||
Unavailable | 9 | 2 (22.2) | 3 (33.3) | 4 (44.4) | |||
Lymph node metastasis | N0 - N1 | 23 | 10 (43.5) | 11 (47.8) | 2 (8.7) | 17.06 | < 0.001 |
N2 - N3 | 33 | 2 (6.1) | 13 (39.4) | 18 (54.5)■ | |||
Unavailable | 9 | 2 (22.2) | 3 (33.3) | 4 (44.4) | |||
pTNM | IA-IIB | 36 | 11 (30.6) | 18 (50) | 7 (19.4) | 12.59 | 0.002 |
IIIA-IV | 20 | 1 (5) | 6 (30) | 13 (65)◆ | |||
Unavailable | 9 | 2 (22.2) | 3 (33.3) | 4 (44.4) | |||