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Table 4 Multiple regression analysis of the relationship between MMP2 and lung cancer

From: Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis

Variables (X)

Categories (different groups)

P value

OR value

95% CI for OR

lower

upper

Gender (X1)

Male (X1–0) vs. female (X1–1)

0.154

0.532

0.223

1.267

Age (X2)

< 60 (X2–0) vs. ≥60 (X2–1)

0.618

0.808

0.422

1.671

Smoking (X3)

No (X3–0) vs. Yes (X32)

0.558

0.810

1.401

1.637

Histology (X4)

LAC (X4–0) vs. LSCC (X41) vs. SCLC (X42)

0.300

0.702

0.360

1.370

Differentiation (X5)

Poor (X5–0) vs. moderate (X5–1) vs. well (X5–2)

0.633

0.620

0.704

1.781

Lymphatic invasion (X6)

N0-N1(X6–0) vs. N2-N3 (X6–1)

0.540

0.485

0.048

4.919

T stage (X7)

T1-T2 (X7–0) vs. T3-T4 (X7–1)

0.307

0.648

0.139

12.32

TNM (X8)

IIA - IIIA (X8–0) vs. IIIB - IV (X8–1)

0.003

2.01

2.013

3.078

MMP2 (X9)

Low (X9–0) vs. moderate (X9–1) vs. high (X9–2)

0.006

1.49

1.012

2.876

Risk function:

H(t) = [h0(t)] e (2.01 X8 + 1.49X9)

  1. LAC lung adenocarcinoma, LSCC lung squamous cell carcinoma, SCLC small cell lung cancer, TNM clinical stage of lung cancer, OR odds ratio, MMP2 matrix metalloproteinase 2, CI confidence interval