|
Case
|
1
|
2
|
3
|
4
|
|---|
|
Age (years)
|
70’s
|
40’s
|
70’s
|
70’s
|
|
Gender
|
Female
|
Female
|
Female
|
Female
|
|
Smoking status
|
Never
|
Never
|
Ex
|
Ex
|
|
Clinical manifestations
|
|
Cough
|
+
|
+
|
+
|
+
|
|
Sputum
|
–
|
+
|
–
|
–
|
|
Dyspnea
|
–
|
+
|
+
|
+
|
|
Xerostomia
|
–
|
–
|
+
|
+
|
|
Xerophthalmia
|
–
|
+
|
+
|
+
|
|
Anti-nuclear antibody
|
80 (centromere)
|
640 (speckled, cytoplasmic)
|
1280 (homogenous)
|
1280 (speckled)
|
|
Anti-SS-A/Ro antibody
|
> 240
|
> 240
|
> 240
|
> 240
|
|
Anti-SS-B/La antibody
|
Negative
|
> 320
|
Negative
|
270.1
|
|
Pulmonary function
|
|
FVC % pred
|
90.9
|
72.1
|
63.9
|
66.4
|
|
FEV1% pred
|
90.3
|
79.4
|
65.5
|
73.3
|
|
FEV1/FVC ratio
|
77.2
|
91.4
|
81.4
|
86.7
|
|
DLCO % pred
|
97.7
|
40.1
|
48.3
|
52.6
|
|
HRCT pattern
|
NSIP
|
UIP + NSIP
|
UIP
|
NSIP+OP
|
|
Salivary gland biopsy
|
grade 3a
|
N/A
|
N/A
|
N/A
|
|
Bronchial gland
|
|
Histopathology grading
|
1
|
2
|
3
|
3
|
|
Duct dilation
|
+
|
+
|
–
|
–
|
- aChisholm-Mason score
- HRCT high-resolution computed tomography, N/A not available
