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Table 3 Baseline characteristics of Sjögren’s syndrome patients

From: Evaluation of lymphocytic infiltration in the bronchial glands of Sjögren’s syndrome in transbronchial lung cryobiopsy

Case 1 2 3 4
Age (years) 70’s 40’s 70’s 70’s
Gender Female Female Female Female
Smoking status Never Never Ex Ex
Clinical manifestations
 Cough + + + +
 Sputum +
 Dyspnea + + +
 Xerostomia + +
 Xerophthalmia + + +
Anti-nuclear antibody 80 (centromere) 640 (speckled, cytoplasmic) 1280 (homogenous) 1280 (speckled)
Anti-SS-A/Ro antibody > 240 > 240 > 240 > 240
Anti-SS-B/La antibody Negative > 320 Negative 270.1
Pulmonary function
 FVC % pred 90.9 72.1 63.9 66.4
 FEV1% pred 90.3 79.4 65.5 73.3
 FEV1/FVC ratio 77.2 91.4 81.4 86.7
 DLCO % pred 97.7 40.1 48.3 52.6
HRCT pattern NSIP UIP + NSIP UIP NSIP+OP
Salivary gland biopsy grade 3a N/A N/A N/A
Bronchial gland
 Histopathology grading 1 2 3 3
 Duct dilation + +
  1. aChisholm-Mason score
  2. HRCT high-resolution computed tomography, N/A not available