Table 3 Baseline characteristics of Sjögren’s syndrome patients
Case | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
Age (years) | 70’s | 40’s | 70’s | 70’s |
Gender | Female | Female | Female | Female |
Smoking status | Never | Never | Ex | Ex |
Clinical manifestations | ||||
Cough | + | + | + | + |
Sputum | – | + | – | – |
Dyspnea | – | + | + | + |
Xerostomia | – | – | + | + |
Xerophthalmia | – | + | + | + |
Anti-nuclear antibody | 80 (centromere) | 640 (speckled, cytoplasmic) | 1280 (homogenous) | 1280 (speckled) |
Anti-SS-A/Ro antibody | > 240 | > 240 | > 240 | > 240 |
Anti-SS-B/La antibody | Negative | > 320 | Negative | 270.1 |
Pulmonary function | ||||
FVC % pred | 90.9 | 72.1 | 63.9 | 66.4 |
FEV1% pred | 90.3 | 79.4 | 65.5 | 73.3 |
FEV1/FVC ratio | 77.2 | 91.4 | 81.4 | 86.7 |
DLCO % pred | 97.7 | 40.1 | 48.3 | 52.6 |
HRCT pattern | NSIP | UIP + NSIP | UIP | NSIP+OP |
Salivary gland biopsy | grade 3a | N/A | N/A | N/A |
Bronchial gland | ||||
Histopathology grading | 1 | 2 | 3 | 3 |
Duct dilation | + | + | – | – |