Correlation between sestrin2 expression and airway remodeling in COPD

BMC Pulmonary Medicine

Table 3 Association between serum sestrin2 concentrations and other measurement indices in COPD group

Test index	r	P value
Serum assay
MMP9(ng/ml)	0.264	0.038^a
Airway parameters on chest CT
Ai8(mm)	0.287	0.024 ^a
A_O (mm²)	0.273	0.032 ^a
WA% (%)	0.294	0.020 ^a
RWT	0.304	0.016 ^a
Pulmonary function
FEV1, L	0.044	0.732^b
FEV1/FVC, %	−0.099	0.444^b
FEV1, % of predicted	0.118	0.359^b

Notes: Correlations were determined by Pearson or Spearman rank correlation analysis
Abbreviations: CT computed tomography, MMP9 matrix metalloproteinases 9, Ai8 Square root of the wall area at an internal airway area of 8 mm², Ao total airway area, WA% wall area percentage, RWT a ratio of airway wall thickness to overall diameter, FVC forced vital capacity, FEV1 forced expiratory volume in one second, a Pearson rank correlation analysis, b Spearman rank correlation analysis, r Pearson or Spearman rank correlation coefficient

ISSN: 1471-2466