Table 1 Patients’ characteristics
Characteristics | ARDS patients (n = 22) | AE-ILD patients (n = 33) | Total patients (n = 55) | P values (ARDS vs. AE-ILDs) |
|---|---|---|---|---|
Age, y | 66.5 ± 10.2 | 75.0 ± 8.0 | 71.4 ± 9.9 | 0.003 |
Male sex | 16 (73) | 21 (72) | 37 (73) | 0.980 |
Aetiology of ARDS | ||||
 Infection | 14 (60) |  | 14 (60) |  |
 Surgery | 5 (23) |  | 5 (23) |  |
 Others | 3 (17) |  | 3 (17) |  |
Diagnosis of ILDs | ||||
 IIPsa |  | 21 (64) | 21 (64) |  |
 CVD-IP |  | 8 (24) | 8 (24) |  |
 Others |  | 4 (12) | 4 (12) |  |
Blood biomarkers | ||||
 P/F ratio | 186.7 ± 103.7 | 219.4 ± 73.8 | 204.4 ± 89.3 | 0.094 |
 Serum LDH, U/L | 368.5 ± 223.0 | 332.7 ± 20.9 | 347.0 ± 168.9 | 0.993 |
 Serum HO-1, ng/mL | 87.8 ± 60.0 | 52.5 ± 36.3 | 66.6 ± 49.9 | 0.011 |
 Serum total bilirubin, mg/dL | 3.9 ± 7.5 | 0.9 ± 0.4 | 2.1 ± 5.0 | 0.090 |
 Serum CRP, mg/dL | 16.6 ± 10.8 | 9.4 ± 6.9 | 12.3 ± 9.3 | 0.008 |
Treatment | ||||
 Corticosteroid use | 13 (59) | 33 (100) | 46 (82) | <  0.001 |
 Corticosteroid pulse use | 3 (14) | 27 (82) | 30 (55) | <  0.001 |
 Frequency of PSL pulse | 1 | 1 (1–4) | 1 (1–4) | 0.304 |
 NEI use | 15 (68) | 11 (33) | 26 (47) | 0.011 |
 Intubation | 22 (100) | 0 (0) | 22 (40) | <  0.001 |
Outcome | ||||
 1-month mortality | 10 (45) | 3 (9) | 13 (24) | <  0.001 |
 3-month mortality | 10 (45) | 8 (24) | 18 (33) | 0.015 |