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Table 1 Population Characteristics by Prior COPD Diagnosis

From: Chronic obstructive pulmonary disease prevalence and prediction in a high-risk lung cancer screening population

Characteristic

Overall Population (N = 2514)

Prior Diagnosis COPD (N = 527)

No Prior Diagnosis COPD (N = 1987)

p-value*

Age, mean (std dev)

62.3 (5.8)

62.1 (6.1)

62.4 (5.8)

0.38

Gender, male, N (%)

1391 (55.3)

253 (48.0)

1138 (57.3)

< 0.001

Education < secondary

405 (16.1)

117 (22.2)

288 (14.5)

< 0.001

 -secondary school

924 (36.8)

191 (36.3)

733 (36.9)

 

 -post-secondary

1185 (47.1)

219 (41.6)

966 (48.6)

 

Pack Years, mean (range)

50 (2.2, 230)

52.5 (2.4, 230)

50 (2.2, 169)

< 0.001

Lung Cancer Risk mean (range)

3.4 (2.0, 38.2)

4.4 (2.0, 34.4)

3.2 (2.0, 38.2)

< 0.001

Current Smoker, n (%)

1566 (62.3)

305 (57.9)

1261 (63.5)

0.020

Dyspnea, n (%)

1133 (45.1)

394 (74.8)

739 (37.2)

< 0.001

Cough, n (%)

1316 (52.4)

361 (68.5)

955 (48.1)

< 0.001

Phlegm, n (%)

1161 (46.2)

329 (62.4)

832 (41.9)

< 0.001

Wheeze, n (%)

943 (37.5)

316 (60.0)

627 (31.6)

< 0.001

Any High Risk Occupation, n (%)

884 (35.2)

198 (37.6)

686 (34.5)

0.20

CXR within 3 years = 0

1017 (40.5)

121 (23.0)

896 (45.1)

< 0.001

 = 1

891 (35.4)

212 (40.2)

679 (34.2)

 

 ≥ 2

606 (24.1)

194 (36.8)

412 (20.7)

 

CT within 3 years = 0

2441 (97.1)

512 (97.2)

1929 (97.1)

0.86

 = 1

68 (2.7)

13 (2.5)

55 (2.8)

 

 = 2

5 (0.2)

2 (0.4)

3 (0.2)

 

Asthma, n (%)

244 (9.7)

117 (22.2)

127 (6.4)

< 0.001

Pulmonary Fibrosis, n (%)

3 (0.1)

1 (0.2)

2 (0.1)

0.51

Pneumonia, n (%)

672 (26.7)

225 (42.7)

447 (22.5)

< 0.001

Respiratory Failure, n (%)

11 (0.4)

8 (1.5)

3 (0.2)

< 0.001

  1. *Comparison of prior diagnosis of COPD to no prior diagnosis of COPD by chi-square (categorical variables) and Wilcoxon rank sum test (continuous)
  2. -Education was collected on a 7 level scale, but grouped here according to secondary and post-secondary completion