Table 2 Changes in respiratory variables during HFNC
Variables | Time (h) | HFNC success | HFNC failure | P |
|---|---|---|---|---|
RR | 2 | 24 (22–26) | 25 (23–27) | 0.138 |
6 | 22 (21–24) | 24 (23–26) | 0.001 | |
12 | 22 (20–25) | 25 (24–25) | 0.002 | |
24 | 21 (20–23) | 25 (25–28) | <0.001 | |
SpO2/FiO2 | 2 | 153.2 (135.6–194.9) | 158.3 (139.8–170.0) | 0.157 |
6 | 158.6 (135.3–215.3) | 123.8 (116.7–157.9) | <0.001 | |
12 | 179.6 (136.1–206.5) | 127.0 (115.3–161.7) | <0.001 | |
24 | 182.7 (142.8–202.1) | 126.4 (116.0–153.8) | <0.001 | |
PaO2/FiO2 | 2 | 116.7 (93.8–143.8) | 111.1 (100.0–125.0) | 0.141 |
6 | 115.4 (100.8–164.3) | 95.3 (83.5–120.3) | <0.001 | |
12 | 130.0 (104.6–168.8) | 90.7 (76.9–106.3) | <0.001 | |
24 | 145.0 (107.2–167.3) | 85.2 (72.9–110.9) | <0.001 | |
ROX index | 2 | 6.8 (5.6–7.8) | 6.4 (4.9–7.6) | 0.074 |
6 | 6.7 (5.9–9.5) | 5.0 (4.6–6.5) | <0.001 | |
12 | 7.9 (6.1–9.1) | 5.0 (4.4–7.3) | <0.001 | |
24 | 7.8 (6.6–10.0) | 4.8 (4.4–6.0) | <0.001 |