Informed consent
| |
x
| | | | | | | |
Eligibility assessment
|
x
|
x
| | | | | | | |
Randomisation
| |
x
| | | | | | | |
Medical history
| |
x
| | | | | | | |
Comorbidities
|
Prior medications
|
APACHE II score
| |
x
| | | | | | | |
SOFA score
| |
x
|
x
|
x
|
x
|
x
| | | |
WHO disease progression scale
| |
x
|
x
| | | |
x
| | |
CRP
| |
x
|
x
|
x
|
x
|
x
| | | |
Viral load (NP or tracheal PCR)
|
Clinical frailty scale
| |
x
| | | | | | | |
Concomitant drugs against SARS-CoV-2
|
x
|
x
|
x
|
x
|
x
|
x
| | | |
Biological findings
| |
xa
|
xb
|
xb
|
x b
|
xb
| | | |
24 h-diuresis
| |
x
|
x
|
x
|
x
|
x
| | | |
Serum sample for central analysis
| |
x
|
x
| | |
x
| |
x
| |
Mechanical ventilation
| |
x
|
x
|
x
|
x
|
x
| | | |
Renal replacement therapy
|
x
|
x
|
x
|
x
|
x
|
Vasoactive drugs
|
x
|
x
|
x
|
x
|
x
|
ECMO
|
x
|
x
|
x
|
x
|
x
|
Nosocomial infections
|
x
|
x
|
x
|
x
|
x
|
Iatrogenic events
|
x
|
x
|
x
|
x
|
x
|
Adverse events & Serious adverse event
| |
x
|
x
|
x
|
x
|
x
| | | |
ADL scale
| |
x
| | | | | |
x
|
x
|
Anxiety-depression scale
| | | | | | | |
x
|
x
|
EQ-5D-5L scale
| |
x
| | | | | |
x
|
x
|