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Table 3 Multivariable logistic regression model for development of COVID-19 in South Korea

From: Impact of coronavirus disease-2019 on chronic respiratory disease in South Korea: an NHIS COVID-19 database cohort study

Variable

Multivariable model

P-value

OR (95% CI)

Chronic respiratory diseases group (model1)

1.04 (0.99, 1.09)

0.156

Chronic respiratory diseases: sensitivity analyses (model2)

  

 COPD

0.96 (0.85, 1.09)

0.553

 Asthma

1.01 (0.96, 1.07)

0.464

 Interstitial lung disease

1.63 (1.17, 2.26)

0.004

 Lung cancer

0.91 (0.67, 1.23)

0.533

 Lung disease d/t external agent

1.35 (0.99, 1.85)

0.061

 Obstructive sleep apnea

1.65 (1.23, 2.16)

 < 0.001

 Tuberculosis of lung

0.92 (0.75, 1.11)

0.372

Age, year

  

 20–29

1

 

 30–39

0.94 (0.86, 1.02)

0.153

 40–49

0.86 (0.80, 0.93)

 < 0.001

 50–59

0.74 (0.69, 0.79)

 < 0.001

 60–69

0.60 (0.55, 0.66)

 < 0.001

 70–79

0.47 (0.42, 0.52)

 < 0.001

 ≥ 80

0.38 (0.33, 0.44)

 < 0.001

Income level

  

 Q1 (Lowest)

1

 

 Q2

0.80 (0.75, 0.86)

 < 0.001

 Q3

0.78 (0.73, 0.83)

 < 0.001

 Q4 (Highest)

0.83 (0.78, 0.88)

 < 0.001

 Unknown

0.75 (0.62, 0.91)

0.004

Sex, male

1.01 (0.96, 1.06)

0.678

Residence

  

 Seoul

1

 

 Gyeonggi-do

0.90 (0.82, 0.99)

0.038

 Daegu

0.96 (0.84, 1.10)

0.562

 Gyeongsangbuk-do

0.94 (0.84, 1.05)

0.271

 Other area

0.89 (0.79, 1.00)

0.053

Underlying disability

1.11 (1.00, 1.22)

0.041

Charlson comorbidity index (model 2)

1.19 (1.18, 1.20)

 < 0.0001

 Hypertension

0.80 (0.74, 0.85)

 < 0.001

 DM without chronic complication

1.75 (1.63, 1.88)

 < 0.001

 DM with chronic complication

0.81 (0.71, 0.92)

0.001

 Peripheral vascular disease

0.75 (0.67, 0.83)

 < 0.001

 Renal disease

0.91 (0.75, 1.11)

0.371

 Rheumatic disease

0.98 (0.85, 1.12)

0.734

 Dementia

1.96 (1.72, 2.22)

 < 0.001

 Peptic ulcer disease

1.48 (1.37, 1.59)

 < 0.001

 Hemiplegia or paraplegia

2.69 (2.11, 3.44)

 < 0.001

 Moderate or severe liver disease

0.59 (0.33, 1.06)

0.076

 Mild liver disease

2.12 (1.99, 2.27)

 < 0.001

 Cerebrovascular disease

0.99 (0.88, 1.11)

0.886

 Congestive heart failure

2.88 (2.60, 3.19)

 < 0.001

 Myocardial infarction

4.55 (3.95, 5.24)

 < 0.001

 Malignancy

2.04 (1.93, 2.15)

 < 0.001

 Metastatic solid tumor

0.95 (0.84, 1.07)

0.387

 AIDS/HIV

4.21 (1.84, 9.64)

 < 0.001

  1. AUC of the multivariable models: 0.81 (95% CI 0.80 to 0.81)
  2. OR, odds ratio; CI, confidence interval; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome; HIV, Human Immunodeficiency Virus